AB122117

Anti-TMEM61 antibody

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(1 Publication)

Rabbit Polyclonal TMEM61 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus.

View Alternative Names

Transmembrane protein 61, TMEM61

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM61 antibody (AB122117)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM61 antibody (AB122117)

ab122117, at 1/200 dilution, staining TMEM61 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q8N0U2

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM61 also known as Transmembrane Protein 61 is a protein encoded by the TMEM61 gene. It has an approximate mass of 21 kDa and spans the membrane suggesting its role as a membrane-associated protein. TMEM61 is expressed widely but exhibits higher expression levels in tissues such as brain and testis. The protein structure suggests potential involvement in signal transmission across cell membranes.

Biological function summary

TMEM61 plays a role in membrane-associated cellular processes. While not much is known about its specific biological functions researchers study it as part of a protein complex that might be integral to maintaining cellular membrane integrity. Evidence suggests TMEM61 could be involved in cellular transport mechanisms owing to its transmembrane nature.

Pathways

TMEM61 could play a part in pathways related to cellular transport and signal transduction. Researchers are investigating its role in the MAPK signaling pathway which involves proteins like ERK1/2. This pathway affects cell division differentiation and stress responses. TMEM61 may interact with other transmembrane proteins influencing these cellular processes.

Current research indicates potential involvement of TMEM61 in neurological disorders possibly linked to its expression in brain tissue. Researchers also examine its role in cancer due to its expression in testis and potential regulation of cell growth. TMEM61 may interact with proteins like PTEN which play roles in tumor suppression and are significant in cancer research.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
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Target data

See full target information TMEM61

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Human molecular genetics 31:1970-1978 PubMed34999892

2022

Mutations in the ribosome biogenesis factor gene LTV1 are linked to LIPHAK syndrome, a novel poikiloderma-like disorder.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Hoon Han,Gavin Ryan,Alyson Guy,Lu Liu,Mathieu Quinodoz,Ingrid Helbling,Joey E Lai-Cheong,Julian Barwell,Marc Folcher,John A McGrath,Celia Moss,Carlo Rivolta

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TMEM61 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM61 antibody (AB122117)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise