Rabbit Polyclonal TMEM61 antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus.
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Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
Liquid
- Clonality
Polyclonal
Immunogen
- Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q8N0U2
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/200.00000 - 1/500.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Alternative names
Transmembrane protein 61, TMEM61
Recommended products
Rabbit Polyclonal TMEM61 antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus.
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
Liquid
- Clonality
Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human TMEM61 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q8N0U2
- Purification technique
Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
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Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
TMEM61 also known as Transmembrane Protein 61 is a protein encoded by the TMEM61 gene. It has an approximate mass of 21 kDa and spans the membrane suggesting its role as a membrane-associated protein. TMEM61 is expressed widely but exhibits higher expression levels in tissues such as brain and testis. The protein structure suggests potential involvement in signal transmission across cell membranes.
- Biological function summary
TMEM61 plays a role in membrane-associated cellular processes. While not much is known about its specific biological functions researchers study it as part of a protein complex that might be integral to maintaining cellular membrane integrity. Evidence suggests TMEM61 could be involved in cellular transport mechanisms owing to its transmembrane nature.
- Pathways
TMEM61 could play a part in pathways related to cellular transport and signal transduction. Researchers are investigating its role in the MAPK signaling pathway which involves proteins like ERK1/2. This pathway affects cell division differentiation and stress responses. TMEM61 may interact with other transmembrane proteins influencing these cellular processes.
- Associated diseases and disorders
Current research indicates potential involvement of TMEM61 in neurological disorders possibly linked to its expression in brain tissue. Researchers also examine its role in cancer due to its expression in testis and potential regulation of cell growth. TMEM61 may interact with proteins like PTEN which play roles in tumor suppression and are significant in cancer research.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM61 antibody (ab122117)
ab122117, at 1/200 dilution, staining TMEM61 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.
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