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AB106099

Anti-TNF Receptor I antibody [55R-170]

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(3 Publications)

Armenian hamster Monoclonal TNF Receptor I antibody. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TNFRSF1A.

View Alternative Names

CD120a, TNFAR, TNFR1, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, p60, TNF-R1, TNF-RI, TNFR-I

Key facts

Host species

Armenian hamster

Clonality

Monoclonal

Clone number

55R-170

Isotype

IgG1

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human TNFRSF1A. The exact immunogen used to generate this antibody is proprietary information.

P19438

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
ab106099 is 0.2 µm filtered.
Storage buffer
Constituents: PBS, 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
See full target information TNFRSF1A

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Annals of the New York Academy of Sciences 1490:77-89 PubMed33543485

2021

Progranulin promotes bone fracture healing via TNFR pathways in mice with type 2 diabetes mellitus.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanjing Ding,Jianlu Wei,Aubryanna Hettinghouse,Guangfei Li,Xin Li,Thomas A Einhorn,Chuan-Ju Liu

PLoS pathogens 16:e1009136 PubMed33370418

2020

Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.

Applications

Unspecified application

Species

Unspecified reactive species

Md Naushad Akhtar,Manish Mishra,Vinod Yadav,Manisha Yadav,Ravindra Gujar,Sunaina Lal,Raj Kumar,Neeraj Khatri,Pradip Sen

The Journal of experimental medicine 181:607-17 PubMed7836916

1995

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

Applications

Unspecified application

Species

Unspecified reactive species

K C Sheehan,J K Pinckard,C D Arthur,L P Dehner,D V Goeddel,R D Schreiber
View all publications

Product promise

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