Rabbit Polyclonal TNF Receptor I antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 121 publications. Immunogen corresponding to Synthetic Peptide within Mouse Tnfrsf1a aa 1-50.
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- Materials today. Bio 23:1008082023Cannabidiol attenuates inflammatory impairment of intestinal cells expanding biomaterial-based therapeutic approaches.Applications:Unspecified applicationReactive species:Unspecified reactive speciesElisa Boehm,Linda Droessler,Salah AmashehPubMed 37779918
- Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 35:66-802023TNFR2 is a potent prognostic biomarker for post-transplant lung metastasis in patients with hepatocellular carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHuigang Li,Zuyuan Lin,Jianyong Zhuo,Modan Yang,Wei Shen,Zhihang Hu,Yichen Ding,Hao Chen,Chiyu He,Xinyu Yang,Siyi Dong,Xuyong Wei,Beicheng Sun,Shusen Zheng,Ren Lang,Di Lu,Xiao XuPubMed 36910852
- Scientific reports 13:25202023Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJulie H Jeon,Erin E Kaiser,Elizabeth S Waters,Xueyuan Yang,Jeferson M Lourenco,Madison M Fagan,Kelly M Scheulin,Sydney E Sneed,Soo K Shin,Holly A Kinder,Anil Kumar,Simon R Platt,Jeongyoun Ahn,Kylee J Duberstein,Michael J Rothrock,Todd R Callaway,Jin Xie,Franklin D West,Hea Jin ParkPubMed 36781906
- International journal of molecular sciences 24:2023Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChiao-Ling Hsu,Yao-Tseng Wen,Tzu-Chao Hsu,Chin-Chu Chen,Li-Ya Lee,Wan-Ping Chen,Rong-Kung TsaiPubMed 36675019
- Glia 71:168-1862022Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLukas Henning,Henrike Antony,Annika Breuer,Julia Müller,Gerald Seifert,Etienne Audinat,Parmveer Singh,Frederic Brosseron,Michael T Heneka,Christian Steinhäuser,Peter BednerPubMed 36373840
- Cell death & disease 13:8852022A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZuoxiang Xiao,Gongping Shi,Sichuan Xi,Amit Kumar Singh,Jami Willette-Brown,Xin Li,Feng Zhu,Ling Su,Xiaolin Wu,David S Schrump,Yinling HuPubMed 36270982
- Journal of orthopaedic translation 36:132-1442022Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-0110634.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWei Ji,Yueyang Lu,Zhuoyi Ma,Ke Gan,Yan Liu,Yue Cheng,Junliang Xu,Shijia Liu,Yunke Guo,Shanhang Han,Zengyan Zhao,Hanmei Xu,Weiyan QiPubMed 36185580
- Frontiers in cardiovascular medicine 9:9423422022Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSilke Griepke,Emilie Grupe,Jes Sanddal Lindholt,Elizabeth Hvitfeldt Fuglsang,Lasse Bach Steffensen,Hans Christian Beck,Mia Dupont Larsen,Sissel Karoline Bang-Møller,Martin Overgaard,Lars Melholt Rasmussen,Kate Lykke Lambertsen,Jane StubbePubMed 36186984
- Molecular metabolism 65:1015822022RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChristopher J Contreras,Noyonika Mukherjee,Renato C S Branco,Li Lin,Meghan F Hogan,Erica P Cai,Andrew A Oberst,Steven E Kahn,Andrew T TemplinPubMed 36030035
- Particle and fibre toxicology 19:482022Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLuiz W Ribeiro,Mathéa Pietri,Hector Ardila-Osorio,Anne Baudry,François Boudet-Devaud,Chloé Bizingre,Zaira E Arellano-Anaya,Anne-Marie Haeberlé,Nicolas Gadot,Sonja Boland,Stéphanie Devineau,Yannick Bailly,Odile Kellermann,Anna Bencsik,Benoit SchneiderPubMed 35840975
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Mouse Tnfrsf1a aa 1-50. The exact immunogen used to generate this antibody is proprietary information. Database link P25118
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1 µg/mL | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1.00000-10.00000 µg/mL | Notes - |
Associated Products
Select an associated product type
5 products for Alternative Product
Target data
Function
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).
Alternative names
CD120a, Tnfr-1, Tnfr1, Tnfrsf1a, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, p60, TNF-R1, TNF-RI, TNFR-I
Recommended products
Rabbit Polyclonal TNF Receptor I antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 121 publications. Immunogen corresponding to Synthetic Peptide within Mouse Tnfrsf1a aa 1-50.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Mouse Tnfrsf1a aa 1-50. The exact immunogen used to generate this antibody is proprietary information. Database link P25118
- Purification technique
- Affinity purification
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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2 product images
Western blot - Anti-TNF Receptor I antibody (ab19139)
All lanes: Western blot - Anti-TNF Receptor I antibody (ab19139) at 1 µg/mL
Lane 1: Heat-shocked HeLa cell lysate
Lane 2: Jurkat cell lysate
Predicted band size: 50 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TNF Receptor I antibody (ab19139)
Immunohistochemistry Formalin/PFA-fixed paraffin-embedded human spleen sections labeling TNF Receptor I with ab19139 at 10ug/mL.
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