AB90463

Anti-TNF Receptor I antibody

(1 Review)

(6 Publications)

Rabbit Polyclonal TNF Receptor I antibody. Suitable for WB and reacts with Human, Saccharomyces cerevisiae samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Mouse Tnfrsf1a.

View Alternative Names

CD120a, TNFAR, TNFR1, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, p60, TNF-R1, TNF-RI, TNFR-I

1 Images

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Western blot - Anti-TNF Receptor I antibody (AB90463)

All lanes:

Western blot - Anti-TNF Receptor I antibody (ab90463) at 1/1000 dilution

Lane 1:

HeLa (heat shocked) cell extract

Lane 2:

Jurkat cell extract

Predicted band size: 50 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human, Saccharomyces cerevisiae

Applications

applications

Immunogen

Synthetic Peptide within Mouse Tnfrsf1a. The exact immunogen used to generate this antibody is proprietary information.

P25118

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Saccharomyces cerevisiae": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

See full target information TNFRSF1A

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroinflammation 18:271 PubMed34789280

2021

TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Li,Yun Cheng,Shenghai Zhang,Xinghuai Sun,Jihong Wu

BioMed research international 2020:9627974 PubMed32964047

2020

Overexpression of miR-29a-3p Suppresses Proliferation, Migration, and Invasion of Vascular Smooth Muscle Cells in Atherosclerosis via Targeting TNFRSF1A.

Applications

Unspecified application

Species

Unspecified reactive species

Liyi You,Hao Chen,Lixin Xu,Xun Li

Frontiers in oncology 10:416 PubMed32296644

2020

Inhibition of microRNA-155 Reduces Neuropathic Pain During Chemotherapeutic Bortezomib via Engagement of Neuroinflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Zongsheng Duan,Jian Zhang,Jing Li,Xiaochuan Pang,Hushan Wang

Molecular pain 15:1744806919857981 PubMed31144562

2019

Roles of tumor necrosis factor-α and interleukin-6 in regulating bone cancer pain via TRPA1 signal pathway and beneficial effects of inhibition of neuro-inflammation and TRPA1.

Applications

Unspecified application

Species

Unspecified reactive species

Ding Zhao,Dong-Feng Han,Si-Si Wang,Bing Lv,Xu Wang,Chi Ma

Cellular physiology and biochemistry : internation 51:2098-2110 PubMed30522101

2018

Blocking TRPA1 and TNF-α Signal Improves Bortezomib-Induced Neuropathic Pain.

Applications

Unspecified application

Species

Unspecified reactive species

Chunrui Li,Taoran Deng,Zhen Shang,Di Wang,Yi Xiao

Frontiers in immunology 8:1468 PubMed29176974

2017

Inhibition of Epithelial TNF-α Receptors by Purified Fruit Bromelain Ameliorates Intestinal Inflammation and Barrier Dysfunction in Colitis.

Applications

Unspecified application

Species

Unspecified reactive species

Zijuan Zhou,Liang Wang,Panpan Feng,Lianhong Yin,Chen Wang,Shengxu Zhi,Jianyi Dong,Jingyu Wang,Yuan Lin,Dapeng Chen,Yongjian Xiong,Jinyong Peng

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TNF Receptor I antibody

Western blot - Anti-TNF Receptor I antibody (AB90463)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise