AB194814

Anti-TNF Receptor I antibody [H398]

Name: Anti-TNF Receptor I antibody [H398] (ab194814) | Abcam
Brand: Abcam Limited
SKU: AB194814
Price: 525 USD
Availability: InStock

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(1 Publication)

Mouse Monoclonal TNF Receptor I antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TNFRSF1A.

View Alternative Names

CD120a, TNFAR, TNFR1, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, p60, TNF-R1, TNF-RI, TNFR-I

2 Images

Flow Cytometry - Anti-TNF Receptor I antibody [H398] (AB194814)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-TNF Receptor I antibody [H398] (AB194814)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab194814 purified antibody at a concentration in sample of 3 μg/mL GAM APC.

Flow Cyt

Supplier Data

Flow Cytometry - Anti-TNF Receptor I antibody [H398] (AB194814)

Separation of human monocytes (red-filled) from CD120a negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab194814 purified antibody at concentration in sample of 3 μg/mL GAM APC.

578 PE

PE Anti-TNF Receptor I antibody [H398]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

H398

Isotype

IgG2a

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human TNFRSF1A.

P19438

Specificity

ab194814 recognizes the extracellular domain of TNF Receptor I. The antibody blocks biological activity of both natural and recombinant Human TNF alpha and TNF beta.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-4 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Purification notes

ab194814 was purified from cell culture supernatant by protein-A affinity chromatography. Purity is> 95% (by SDS-PAGE).

Storage buffer

pH: 7.4 Preservative: 0.095% Sodium azide Constituents: 99% PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

See full target information TNFRSF1A

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 2:261 PubMed31341960

2019

Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy.

Applications

Unspecified application

Species

Unspecified reactive species

Gerti Beliu,Andreas J Kurz,Alexander C Kuhlemann,Lisa Behringer-Pliess,Mara Meub,Natalia Wolf,Jürgen Seibel,Zhen-Dan Shi,Martin Schnermann,Jonathan B Grimm,Luke D Lavis,Sören Doose,Markus Sauer

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TNF Receptor I antibody [H398]

Flow Cytometry - Anti-TNF Receptor I antibody [H398] (AB194814)

Flow Cytometry - Anti-TNF Receptor I antibody [H398] (AB194814)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

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