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AB233407

Anti-TOM70 antibody

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(1 Publication)

Rabbit Polyclonal TOM70 antibody. Suitable for WB, IHC-P and reacts with Pig, Human, Recombinant full length protein - Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TOMM70 aa 300 to C-terminus.

View Alternative Names

KIAA0719, TOM70, TOMM70A, TOMM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, Translocase of outer mitochondrial membrane protein 70

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TOM70 antibody (AB233407)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TOM70 antibody (AB233407)

Paraffin-embedded human liver tissue stained for TOM70 using ab233407 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TOM70 antibody (AB233407)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TOM70 antibody (AB233407)

Paraffin-embedded human cerebrum tissue stained for TOM70 using ab233407 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-TOM70 antibody (AB233407)
  • WB

Supplier Data

Western blot - Anti-TOM70 antibody (AB233407)

All lanes:

Western blot - Anti-TOM70 antibody (ab233407) at 1 µg/mL

Lane 1:

Pig brain lysate

Lane 2:

Pig liver lysate

Lane 3:

Pig heart lysate

Lane 4:

Mouse brain lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 67 kDa

false

Western blot - Anti-TOM70 antibody (AB233407)
  • WB

Supplier Data

Western blot - Anti-TOM70 antibody (AB233407)

All lanes:

Western blot - Anti-TOM70 antibody (ab233407) at 1 µg/mL

All lanes:

Recombinant human TOM70 protein

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 67 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human, Pig

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human TOMM70 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O94826

Reactivity data

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab233407 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed : 12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed : 12526792, PubMed : 35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed : 20628368, PubMed : 25609812, PubMed : 32728199). Upon Sendai virus infection, recruits HSP90AA1 : IRF3 : BAX in mitochondrion and the complex induces apoptosis (PubMed : 25609812).
See full target information TOMM70

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 26:107891 PubMed37766980

2023

Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis.

Applications

Unspecified application

Species

Unspecified reactive species

Mick J M van Eijs,José J M Ter Linde,Matthijs J D Baars,Mojtaba Amini,Miangela M Laclé,Eelco C Brand,Eveline M Delemarre,Julia Drylewicz,Stefan Nierkens,Rik J Verheijden,Bas Oldenburg,Yvonne Vercoulen,Karijn P M Suijkerbuijk,Femke van Wijk
View all publications

Product promise

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