AB89624

Anti-TOM70 antibody

Name: Anti-TOM70 antibody (ab89624) | Abcam
Brand: Abcam Limited
SKU: AB89624
Rating: 5 (1 reviews)

(1 Review)

(6 Publications)

Mouse Polyclonal TOM70 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TOMM70.

View Alternative Names

KIAA0719, TOM70, TOMM70A, TOMM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, Translocase of outer mitochondrial membrane protein 70

3 Images

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

All lanes:

HepG2 cell lysate at 50 µg

Predicted band size: 67 kDa

Observed band size: 75 kDa

false

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

Lane 1:

TOMM70A transfected 293T cell lysate at 25 µg

Lane 2:

Non transfected 293T cell lysate at 25 µg

Predicted band size: 67 kDa

Observed band size: 75 kDa

false

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

All lanes:

human liver tissue lysate at 50 µg

Predicted band size: 67 kDa

Observed band size: 67 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human TOMM70.

O94826

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed : 12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed : 12526792, PubMed : 35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed : 20628368, PubMed : 25609812, PubMed : 32728199). Upon Sendai virus infection, recruits HSP90AA1 : IRF3 : BAX in mitochondrion and the complex induces apoptosis (PubMed : 25609812).

See full target information TOMM70

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Endocrinology 164: PubMed37586092

2023

Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Michele R Plewes,Heather A Talbott,Anthony J Saviola,Nicholas T Woods,Micah B Schott,John S Davis

Frontiers in aging neuroscience 14:1013943 PubMed36408108

2022

Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Xi Cao,Yanting Chen,Xiaoyu Sang,Shunliang Xu,Zhaohong Xie,Zhengyu Zhu,Ping Wang,Jianzhong Bi,Linlin Xu

Frontiers in cell and developmental biology 8:617762 PubMed33537307

2021

Interplay Between Mitophagy and Apoptosis Defines a Cell Fate Upon Co-treatment of Breast Cancer Cells With a Recombinant Fragment of Human κ-Casein and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand.

Applications

Unspecified application

Species

Unspecified reactive species

Fabian Wohlfromm,Max Richter,Lado Otrin,Kamil Seyrek,Tanja Vidaković-Koch,Elena Kuligina,Vladimir Richter,Olga Koval,Inna N Lavrik

PLoS genetics 16:e1008923 PubMed32735630

2020

RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.

Applications

Unspecified application

Species

Unspecified reactive species

Aurelio Reyes,Paola Favia,Sara Vidoni,Vittoria Petruzzella,Massimo Zeviani

Cancers 12: PubMed32486420

2020

The Recombinant Fragment of Human κ-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Max Richter,Fabian Wohlfromm,Thilo Kähne,Hannes Bongartz,Kamil Seyrek,Yuriy Kit,Olga Chinak,Vladimir A Richter,Olga A Koval,Inna N Lavrik

The Journal of biological chemistry 288:2223-37 PubMed23212910

2012

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

Applications

Species

Human

Aleksandar Rakovic,Katharina Shurkewitsch,Philip Seibler,Anne Grünewald,Alessandra Zanon,Johann Hagenah,Dimitri Krainc,Christine Klein

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TOM70 antibody

Western blot - Anti-TOM70 antibody (AB89624)

Western blot - Anti-TOM70 antibody (AB89624)

Western blot - Anti-TOM70 antibody (AB89624)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise