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AB13518

Anti-TPN antibody

5

(1 Review)

|

(8 Publications)

Rabbit Polyclonal TPN antibody. Suitable for IP, WB and reacts with Human samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human TAPBP aa 400 to C-terminus.

View Alternative Names

NGS17, TAPA, TAPBP, Tapasin, TPN, TPSN, NGS-17, TAP-associated protein, TAP-binding protein

1 Images
Western blot - Anti-TPN antibody (AB13518)
  • WB

Supplier Data

Western blot - Anti-TPN antibody (AB13518)

All lanes:

Western blot - Anti-TPN antibody (ab13518) at 1/1000 dilution

All lanes:

A431 lysate

Predicted band size: 48 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, WB

applications

Immunogen

Synthetic Peptide within Human TAPBP aa 400 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O15533

Specificity

Weakly cross-reacts with bovine Tapasin.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Cow": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
See full target information TAPBP
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Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Oncoimmunology 13:2370928 PubMed38948930

2024

Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Wang,Barbara Seliger

Frontiers in immunology 13:992060 PubMed36311733

2022

An antigen processing and presentation signature for prognostic evaluation and immunotherapy selection in advanced gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ke-Wei Wang,Mei-Dan Wang,Zi-Xi Li,Ben-Shun Hu,Jun-Jie Wu,Zheng-Dong Yuan,Xiao-Long Wu,Qin-Fang Yuan,Feng-Lai Yuan

Nature communications 13:4701 PubMed35948544

2022

Molecular basis of MHC I quality control in the peptide loading complex.

Applications

Unspecified application

Species

Unspecified reactive species

Alexander Domnick,Christian Winter,Lukas Sušac,Leon Hennecke,Mario Hensen,Nicole Zitzmann,Simon Trowitzsch,Christoph Thomas,Robert Tampé

Scientific reports 11:9080 PubMed33907276

2021

Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing.

Applications

Unspecified application

Species

Unspecified reactive species

Yi-Hsin Liang,Jia-Huei Tsai,Yung-Ming Cheng,Kuang-Yu Chan,Wen-Ling Hsu,Chang-Cheng Lee,Kuo-Hsing Chen,Kun-Huei Yeh

Oncoimmunology 9:1774323 PubMed32923135

2020

Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.

Applications

Unspecified application

Species

Unspecified reactive species

Maria-Filothei Lazaridou,Evamaria Gonschorek,Chiara Massa,Michael Friedrich,Diana Handke,Anja Mueller,Simon Jasinski-Bergner,Reinhard Dummer,Peter Koelblinger,Barbara Seliger

Journal of immunology (Baltimore, Md. : 1950) 196:4468-76 PubMed27183594

2016

Characterization of the Antigen Processing Machinery and Endogenous Peptide Presentation of a Bat MHC Class I Molecule.

Applications

Unspecified application

Species

Unspecified reactive species

James W Wynne,Amanda P Woon,Nadine L Dudek,Nathan P Croft,Justin H J Ng,Michelle L Baker,Lin-Fa Wang,Anthony W Purcell

Cancer gene therapy 21:317-32 PubMed24971583

2014

Adenovirus expressing β2-microglobulin recovers HLA class I expression and antitumor immunity by increasing T-cell recognition.

Applications

Unspecified application

Species

Unspecified reactive species

A B Del Campo,J Carretero,J A Muñoz,S Zinchenko,F Ruiz-Cabello,G González-Aseguinolaza,F Garrido,N Aptsiauri

Journal of immunology (Baltimore, Md. : 1950) 176:1053-61 PubMed16393993

2006

Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation.

Applications

WB

Species

Human

Jacques Chapiro,Stéphane Claverol,Fanny Piette,Wenbin Ma,Vincent Stroobant,Benoît Guillaume,Jean-Edouard Gairin,Sandra Morel,Odile Burlet-Schiltz,Bernard Monsarrat,Thierry Boon,Benoît J Van den Eynde
View all publications
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