Anti-TRIM31 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

TRIM31 functions in cellular processes such as the innate immune response and cell proliferation. It interacts with important cellular complexes that modulate innate immunity signifying its contribution to antiviral responses. TRIM31 regulates the degradation of certain proteins involved in these processes which can influence how cells respond to viral infections or cellular stress. Furthermore by controlling protein turnover TRIM31 contributes to cellular homeostasis and defense mechanisms against pathogens.

Pathways

TRIM31 has significant involvement in the NF-κB signaling pathway as well as the autophagy pathway. Within the NF-κB pathway TRIM31 can influence the activity of key proteins like IκBα by tagging them for degradation which in turn affects NF-κB activity and controls inflammatory responses. In the autophagy pathway TRIM31 associates with proteins like Beclin1 where it plays a role in modulating autophagic flux and maintaining cellular homeostasis during stress conditions.