JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB224104

Anti-TSGA2 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal TSGA2 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human RSPH1 aa 100-250.

View Alternative Names

TSA2, TSGA2, RSPH1, Radial spoke head 1 homolog, Cancer/testis antigen 79, Male meiotic metaphase chromosome-associated acidic protein, Meichroacidin, Testis-specific gene A2 protein, CT79

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TSGA2 antibody (AB224104)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TSGA2 antibody (AB224104)

Paraffin-embedded human Fallopian tube tissue stained for TSGA2 with ab224104 (1/50) in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TSGA2 antibody (AB224104)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TSGA2 antibody (AB224104)

Paraffin-embedded human testis tissue stained for TSGA2 with ab224104 (1/50) in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human RSPH1 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.

Q8WYR4

style
left-column

Alternative Products

Primary Antibodies

AB224386

Anti-TSGA2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TSGA2 antibody (AB224386)

  • 0
  • 0

Complementary Products

Primary Antibodies

AB236386

Anti-GAS8 antibody [OTI10G2]

Western blot - Anti-GAS8 antibody [OTI10G2] (AB236386)

  • 0
  • 0
Primary Antibodies

AB223045

Anti-RSPH9 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RSPH9 antibody (AB223045)

  • 0
  • 0
Primary Antibodies

AB122157

Anti-RSPH4A antibody

Immunocytochemistry/ Immunofluorescence - Anti-RSPH4A antibody (AB122157)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TSGA2 also known as testis-specific gene antigen 2 is a protein encoded by the TSGA2 gene. Its molecular mass is approximately 67 kDa. TSGA2 shows high expression in testicular tissues indicating a role related to reproductive biology. It is less often found in other tissues under normal conditions which suggests a specialized function in male germ cells.
Biological function summary

TSGA2 plays a role in the organization of cellular structures during spermatogenesis. This protein participates in the formation of sperm-specific elements. TSGA2 potentially interacts with components of the cytoskeleton facilitating the organized shape and function of mature sperm.

Pathways

TSGA2 integrates within the spermatogenesis process. The protein contributes to the structure and motility development of spermatozoa associating with proteins involved in microtubule dynamics such as tubulins. It functions alongside dynein and kinesin which are motor proteins critical for movement within cells ensuring sperm development happens correctly.

TSGA2 has connections to infertility specifically that which affects spermatogenesis. Abnormal expression or mutations in TSGA2 can disrupt normal sperm development leading to reduced fertility in males. Some studies suggest links with proteins like DAZL another important player in germ cell regulation appealing as a potential area for exploring diagnostic and therapeutic avenues in male infertility.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.
See full target information RSPH1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 7:1649 PubMed39702755

2024

Methylation-modulated PFTK1 regulates gefitinib resistance via Wnt/β-catenin signaling in EGFR mutant non-small-cell lung cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoting Jia,Jingjie Tian,Pingping Chen,Jing Dong,Lei Li,Danyang Chen,Jianlei Zhang,Dongjiang Liao,Zhimin He,Kai Luo
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com