Anti-TSPYL5 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The TSPYL5 protein also known as Testis-Specific Y-encoded-Like Protein 5 plays a role as a transcription regulator. It is encoded by the TSPYL5 gene and has a molecular mass of approximately 70 kDa. TSPYL5 is expressed in various human tissues with higher levels detected in the testis brain and epithelial tissues. Researchers have noted its presence in different cancer cell lines highlighting its significance in cancer research.

Biological function summary

The functions of TSPYL5 impact cellular processes including cell growth and survival. While not recognized as part of a specific protein complex TSPYL5 appears to influence transcriptional regulation by interacting with other molecular players. It shows interaction with chromatin and may modulate gene expression patterns that are important for cellular homeostasis.

Pathways

TSPYL5 integrates into pathways that regulate cellular proliferation and apoptosis. The protein plays a role within the stress-induced transcriptional regulation pathway and the cell cycle control pathway. In these contexts it can interact with other key proteins such as p53 and HDAC1 influencing the cellular response to various internal and external stimuli.

Associated diseases and disorders

TSPYL5 has connections to cancer development especially in prostate and breast cancer. The protein might contribute to tumorigenesis by altering gene expression profiles that control cell cycle and apoptosis linking it with common oncogenes and tumor suppressors. These activities connect TSPYL5 to proteins such as p21 and RB1 which are also involved in regulating cell growth and death highlighting its role as a potential therapeutic target in cancer treatment.