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AB214216

Anti-TUBD1 antibody

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(1 Publication)

Rabbit Polyclonal TBD antibody. Suitable for WB and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human TUBD1 aa 150-250 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

TUBD, TUBD1, Tubulin delta chain, Delta-tubulin

1 Images
Western blot - Anti-TUBD1 antibody (AB214216)
  • WB

Supplier Data

Western blot - Anti-TUBD1 antibody (AB214216)

All lanes:

Western blot - Anti-TUBD1 antibody (ab214216) at 1/300 dilution

All lanes:

mouse heart lysate

Secondary

All lanes:

Goat Anti-Rabbit IgG Antibody (H+L), HRP at 1/5000 dilution

Predicted band size: 51 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

WB

applications

Immunogen

Synthetic Peptide within Human TUBD1 aa 150-250 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9UJT1

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Secondary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/100 - 1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Tubulin Delta 1 (TUBD1) protein also known as C20orf23 is involved in microtubule dynamics as part of the tubulin superfamily. TUBD1 has a molecular mass of approximately 53 kDa. It is expressed in various tissues throughout the body with a notable presence in the brain and skeletal muscle. It contributes to the assembly of microtubules by incorporating into the tubulin heterodimers which are the basic building blocks necessary for microtubule formation.
Biological function summary

The protein plays a fundamental role in mitotic spindle formation and chromosome segregation during cellular division. TUBD1 acts as a component of the multiprotein complexes that interact with other microtubules to ensure stability and proper organization within the cell. The correct functioning of TUBD1 is necessary for maintaining the integrity of the mitotic processes that are important for normal cell cycle progression. It also interfaces with several signaling pathways that regulate cell growth and proliferation.

Pathways

TUBD1 participates in the regulation of the cell cycle and microtubule-associated pathways. It is essential for the mitotic spindle assembly checkpoint pathway and is related to other tubulin family proteins such as beta-tubulin and gamma-tubulin. These relationships help facilitate the cross-talk needed for initiating the proper steps in the progression of mitosis ensuring cellular health and division accuracy.

TUBD1 has been implicated in various cancers and neurodegenerative disorders. Abnormalities in TUBD1 expression or function may contribute to the development of malignancies due to its role in cell division and structure. Disruptions in TUBD1 function can also relate to neurodegenerative diseases as its action is intertwined with neuronal cell stability. In cancer alterations in TUBD1 function can be linked with mutations in other regulatory proteins like p53 which oversees cell cycle progression highlighting its relevance in oncogenesis.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
See full target information TUBD1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

PLoS genetics 13:e1007078 PubMed29136647

2017

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse.

Applications

Unspecified application

Species

Unspecified reactive species

Jessica E M Dunleavy,Hidenobu Okuda,Anne E O'Connor,D Jo Merriner,Liza O'Donnell,Duangporn Jamsai,Martin Bergmann,Moira K O'Bryan
View all publications
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Product promise

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