AB89626

Anti-Vitamin D Receptor antibody

Name: Anti-Vitamin D Receptor antibody (ab89626) | Abcam
Brand: Abcam Limited
SKU: AB89626
Rating: 5 (2 reviews)

(2 Reviews)

(3 Publications)

Mouse Polyclonal Vitamin D Receptor antibody. Carrier free. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human VDR.

View Alternative Names

NR1I1, VDR, Vitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

3 Images

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor antibody (AB89626)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor antibody (AB89626)

ab89626 at 10μl/ml staining Vitamin D Receptor on HeLa cell by immunofluorescence

Unknown

Western blot - Anti-Vitamin D Receptor antibody (AB89626)

All lanes:

Western blot - Anti-Vitamin D Receptor antibody (ab89626) at 1 µg/mL

Lane 1:

Vitamin D Receptor transfected 293T cell lysate at 25 µg

Lane 2:

Non-transfected 293T cell lysate at 25 µg

Predicted band size: 48 kDa

Observed band size: 48 kDa

false

Unknown

Western blot - Anti-Vitamin D Receptor antibody (AB89626)

All lanes:

Western blot - Anti-Vitamin D Receptor antibody (ab89626) at 1 µg/mL

All lanes:

293 Cell lysate at 50 µg

Predicted band size: 48 kDa

Observed band size: 48 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human VDR.

P11473

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed : 10678179, PubMed : 15728261, PubMed : 16913708, PubMed : 28698609, PubMed : 37478846). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed : 28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed : 28698609). Plays a central role in calcium homeostasis (By similarity). Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed : 12016314, PubMed : 32354638).

See full target information VDR

style

left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Annals of translational medicine 10:506 PubMed35928745

2022

High sodium reduced the expression of PTH1R and Klotho by inhibiting 1,25(OH)D synthesis in cultured proximal tubule epithelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Gu,Jialin Shi,Xujiao Chen,Jianping Mao,Huaizhou You,Jing Chen

Cell & bioscience 12:98 PubMed35765066

2022

DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritis.

Applications

Unspecified application

Species

Unspecified reactive species

Haochen Guan,Nan Zhu,Gang Tang,Yi Du,Ling Wang,Weijie Yuan

PloS one 8:e59842 PubMed23555801

2013

BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Manuel Bernal-Quirós,Ying-Yu Wu,Marta E Alarcón-Riquelme,Casimiro Castillejo-López

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Vitamin D Receptor antibody

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor antibody (AB89626)

Western blot - Anti-Vitamin D Receptor antibody (AB89626)

Western blot - Anti-Vitamin D Receptor antibody (AB89626)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

Alternative Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise