AB63572

Anti-Vitamin D Receptor (phospho S208) antibody

Name: Anti-Vitamin D Receptor (phospho S208) antibody (ab63572) | Abcam
Brand: Abcam Limited
SKU: AB63572
Price: 525 USD
Availability: InStock

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(1 Publication)

Rabbit Polyclonal Vitamin D Receptor phospho S208 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human VDR phospho S208.

View Alternative Names

NR1I1, VDR, Vitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor (phospho S208) antibody (AB63572)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor (phospho S208) antibody (AB63572)

Immunofluorescent staining of A549 cells, using ab63572 at a 1/500 dilution, minus immunising peptide (left image) and plus immunising peptide (right image).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Synthetic Peptide within Human VDR phospho S208. The exact immunogen used to generate this antibody is proprietary information.

P11473

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/500 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed : 10678179, PubMed : 15728261, PubMed : 16913708, PubMed : 28698609, PubMed : 37478846). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed : 28698609). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (PubMed : 28698609). Plays a central role in calcium homeostasis (By similarity). Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed : 12016314, PubMed : 32354638).

See full target information VDR phospho S208

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of experimental medicine 207:731-50 PubMed20368581

2010

Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia.

Applications

Species

Human

Celine Callens,Séverine Coulon,Jerome Naudin,Isabelle Radford-Weiss,Nicolas Boissel,Emmanuel Raffoux,Pamella Huey Mei Wang,Saurabh Agarwal,Houda Tamouza,Etienne Paubelle,Vahid Asnafi,Jean-Antoine Ribeil,Philippe Dessen,Danielle Canioni,Olivia Chandesris,Marie Therese Rubio,Carole Beaumont,Marc Benhamou,Hervé Dombret,Elizabeth Macintyre,Renato C Monteiro,Ivan C Moura,Olivier Hermine

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Vitamin D Receptor (phospho S208) antibody

Immunocytochemistry/ Immunofluorescence - Anti-Vitamin D Receptor (phospho S208) antibody (AB63572)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (1)

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