Mouse Monoclonal Vitronectin/S-Protein antibody. Suitable for Flow Cyt, WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Vitronectin aa 1-200.
Images
![Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--western-blot-img57199.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981)")
![Flow Cytometry - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--flow-cytometry-img121693.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img116480.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img108448.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981)")
![Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--western-blot-img36512.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (AB201981)")
Publications
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- The Journal of cell biology 221:2022Integrin-based adhesion compartmentalizes ALK3 of the BMPRII to control cell adhesion and migration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAmaris Guevara-Garcia,Laure Fourel,Ingrid Bourrin-Reynard,Adria Sales,Christiane Oddou,Mylène Pezet,Olivier Rossier,Paul Machillot,Line Chaar,Anne-Pascale Bouin,Gregory Giannone,Olivier Destaing,Catherine Picart,Corinne Albiges-RizoPubMed 36205720
- Viruses 14:2021Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCandace R Fox,Griffith D ParksPubMed 35062233
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Fragment Protein within Human Vitronectin aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link P04004
Abcam Recommends
Reactivity data
Select an application| Flow Cyt | WB | IHC-P | |
|---|---|---|---|
| Human | Tested | Tested | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/200.00000 - 1/400.00000 | Notes ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/2000.00000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/200.00000 - 1/1000.00000 | Notes - |
Associated Products
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Target data
Function
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
Alternative names
Vitronectin, VN, S-protein, Serum-spreading factor, V75, VTN
Recommended products
Mouse Monoclonal Vitronectin/S-Protein antibody. Suitable for Flow Cyt, WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Vitronectin aa 1-200.
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Fragment Protein within Human Vitronectin aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link P04004
- Clone number
- 1G11E8
- Purification technique
- Affinity purification Protein G
- Concentration
- Purification notes
Purified from tissue culture supernatant.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
5 product images
![Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--western-blot-img57199.jpg "Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)")
Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)
All lanes: Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981) at 1/500 dilution
Lane 1: HEK293 cell lysate
Lane 2: Vitronectin/S-Protein (AA: 20-199)-hIgGFc transfected HEK293 cell lysate
Predicted band size: 54 kDa
![Flow Cytometry - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--flow-cytometry-img121693.jpg "Flow Cytometry - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)")
Flow Cytometry - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)
Flow cytometric analysis of Hela cells labeling Vitronectin/S-Protein using ab201981 at 1/200 dilution (green) and negative control (red).
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img116480.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling Vitronectin/S-Protein with ab201981 at 1/200 dilution with DAB staining
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img108448.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Vitronectin/S-Protein with ab201981 at 1/200 dilution with DAB staining.
![Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981), expandable thumbnail](https://content.abcam.com/products/images/vitronectin-s-protein-antibody-1g11e8-ab201981--western-blot-img36512.jpg "Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)")
Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981)
All lanes: Western blot - Anti-Vitronectin/S-Protein antibody [1G11E8] (ab201981) at 1/500 dilution
All lanes: Human Vitronectin/S-Protein (AA: 20-199) recombinant protein
Predicted band size: 54 kDa
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