AB778

Anti-Von Willebrand Factor antibody [F8/86]

Name: Anti-Von Willebrand Factor antibody [F8/86] (ab778) | Abcam
Brand: Abcam Limited
SKU: AB778
Price: 450 USD
Availability: InStock
Rating: 3 (3 reviews)

(3 Reviews)

(16 Publications)

Mouse Monoclonal Von Willebrand Factor antibody. Suitable for IHC-Fr, IHC-P and reacts with Human samples. Cited in 16 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human VWF.

View Alternative Names

F8VWF, VWF, von Willebrand factor, vWF

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Von Willebrand Factor antibody [F8/86] (AB778)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Von Willebrand Factor antibody [F8/86] (AB778)

Formalin fixed paraffin embedded human tonsil tissue, staining von Willebrand factor with ab778 in immunohistochemical analysis

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

F8/86

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

IHC-P, IHC-Fr

applications

Immunogen

Native Full Length Protein corresponding to Human VWF.

P04275

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p>ABC method. We suggest an incubation period of 60 minutes at room temperature.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/50", "IHCP-species-notes": "<p></p> Perform enzymatic antigen retrieval before commencing with IHC staining protocol." } } }

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.3 - 7.5 Preservative: 0.05% Sodium azide Constituents: Tissue culture supernatant, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

See full target information VWF

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Publications (16)

Recent publications for all applications. Explore the full list and refine your search

Cell death discovery 11:200 PubMed40280907

2025

The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Ramla Omar,Michelle Aw Lee,Laura Gonzalez-Trueba,Cameron R Thomson,Uwe Hansen,Spyridonas Lianos,Snoopy Hazarika,Omar Hmeh El Abdallah,Malak A Ammar,Jennifer Cassels,Alison M Michie,Neil J Bulleid,Fransiska Malfait,Tom Van Agtmael

Frontiers in bioengineering and biotechnology 10:894956 PubMed36406232

2022

A proteomics analysis of neointima formation on decellularized vascular grafts reveals regenerative alterations in protein signature running head: Proteomics analysis of neointima formation.

Applications

Unspecified application

Species

Unspecified reactive species

Chunyang Chen,Ting Lu,Zhongshi Wu,Xinlong Xie,Yalin Liu,Can Huang,Yuhong Liu

Translational andrology and urology 11:761-772 PubMed35812200

2022

Three new experimental models of anterior urethral stricture in rabbits.

Applications

Unspecified application

Species

Unspecified reactive species

Hai-Jun Yao,Zi-Wei Wei,Xiang Wan,Yu-Cheng Tao,Da-Chao Zheng,Zhong Wang,Min-Kai Xie

Annals of translational medicine 9:232 PubMed33708859

2021

MiR-4729 regulates TIE1 mRNA m6A modification and angiogenesis in hemorrhoids by targeting METTL14.

Applications

Unspecified application

Species

Unspecified reactive species

Te Liu,Haikun Zhou,Hong Lu,Chunsheng Luo,Qingming Wang,Yunhua Peng,Wei Yang,Yaojie Xin

Stem cell research & therapy 11:535 PubMed33308306

2020

Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis.

Applications

Unspecified application

Species

Unspecified reactive species

Xiang Wan,Min-Kai Xie,Huan Xu,Zi-Wei Wei,Hai-Jun Yao,Zhong Wang,Da-Chao Zheng

American journal of translational research 10:3053-3067 PubMed30416650

2018

Inducible pluripotent stem cell-derived mesenchymal stem cell therapy effectively protected kidney from acute ischemia-reperfusion injury.

Applications

Unspecified application

Species

Unspecified reactive species

Sheung-Fat Ko,Yen-Ta Chen,Christopher Glenn Wallace,Kuan-Hung Chen,Pei-Hsun Sung,Ben-Chung Cheng,Tien-Hung Huang,Yi-Ling Chen,Yi-Chen Li,Hsueh-Wen Chang,Mel S Lee,Chih-Chao Yang,Hon-Kan Yip

Experimental cell research 370:333-342 PubMed29964051

2018

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Zhang,Xiaozhi Bai,Bin Zhao,Yan Li,Yijie Zhang,Zhenzhen Li,Xujie Wang,Liang Luo,Fu Han,Julei Zhang,Shichao Han,Weixia Cai,Linlin Su,Ke Tao,Jihong Shi,Dahai Hu

Molecular medicine reports 17:1651-1659 PubMed29257200

2017

Protective effects of atorvastatin on cerebral vessel autoregulation in an experimental rabbit model of subarachnoid hemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Jun-Hui Chen,Ting Wu,Li-Kun Yang,Lei Chen,Jie Zhu,Pei-Pei Li,Xu Hu,Yu-Hai Wang

Molecular medicine reports 14:234-42 PubMed27151366

2016

The transplantation of Akt-overexpressing amniotic fluid-derived mesenchymal stem cells protects the heart against ischemia-reperfusion injury in rabbits.

Applications

IHC-P

Species

Rabbit

Yan Wang,Yigang Li,Lei Song,Yanyan Li,Shan Jiang,Song Zhang

Biomaterials 44:134-42 PubMed25617133

2015

Synergistic effect of laminin and mesenchymal stem cells on tracheal mucosal regeneration.

Applications

IHC-P

Species

Rabbit

Doh Young Lee,Jin Ho Lee,Hee-Jin Ahn,Se Heang Oh,Tae Ho Kim,Hee-Bok Kim,Seok-Won Park,Seong Keun Kwon

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Von Willebrand Factor antibody [F8/86]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Von Willebrand Factor antibody [F8/86] (AB778)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (16)

Product promise