Rabbit Polyclonal VPAC2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 11 publications. Immunogen corresponding to Synthetic Peptide within Human VIPR2 aa 400 to C-terminus conjugated to Keyhole Limpet Haemocyanin.
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Publications
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- Nature communications 12:57632021Circadian neurons in the paraventricular nucleus entrain and sustain daily rhythms in glucocorticoids.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJeff R Jones,Sneha Chaturvedi,Daniel Granados-Fuentes,Erik D HerzogPubMed 34599158
- Neuron 108:164-179.e72020Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYongli Shan,John H Abel,Yan Li,Mariko Izumo,Kimberly H Cox,Byeongha Jeong,Seung-Hee Yoo,David P Olson,Francis J Doyle,Joseph S TakahashiPubMed 32768389
- PloS one 14:e02114332019VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesIvan Ivic et. al.PubMed 30682157
- The Journal of neuroscience : the official journal 38:7986-79952018SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJeff R Jones et. al.PubMed 30082421
- Proceedings of the National Academy of Sciences of 115:E3296-E33042018mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDong Liu et. al.PubMed 29555746
- The British journal of dermatology 175:531-412016Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse.Applications:Unspecified applicationReactive species:Unspecified reactive speciesM Bertolini,M Pretzlaff,M Sulk,M Bähr,J Gherardini,Y Uchida,M Reibelt,M Kinori,A Rossi,T Bíró,R PausPubMed 27059672
- Nature communications 7:105832016Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMasao Doi et. al.PubMed 26882873
- International journal of molecular sciences 16:17344-672015Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTamás Juhász et. al.PubMed 26230691
- The Journal of neuroscience : the official journal of the Society for Neuroscience 34:6040-62014Vasoactive intestinal polypeptide mediates circadian rhythms in mammalian olfactory bulb and olfaction.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJae-Eun Kang Miller,Daniel Granados-Fuentes,Thomas Wang,Luciano Marpegan,Timothy E Holy,Erik D HerzogPubMed 24760863
- The Journal of comparative neurology 520:2730-412012Spatiotemporal distribution of vasoactive intestinal polypeptide receptor 2 in mouse suprachiasmatic nucleus.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSungwon An,Connie Tsai,Julie Ronecker,Alison Bayly,Erik D HerzogPubMed 22684939
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.05% Sodium azide
Constituents: Whole serum- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human VIPR2 aa 400 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link P41587
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Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/250 - 1/500 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 | Notes - |
Associated Products
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2 products for Alternative Product
Target data
Function
This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
Alternative names
VIP2R, VIPR2, Vasoactive intestinal polypeptide receptor 2, VIP-R-2, Helodermin-preferring VIP receptor, Pituitary adenylate cyclase-activating polypeptide type III receptor, VPAC2, PACAP type III receptor, PACAP-R-3, PACAP-R3
Recommended products
Rabbit Polyclonal VPAC2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 11 publications. Immunogen corresponding to Synthetic Peptide within Human VIPR2 aa 400 to C-terminus conjugated to Keyhole Limpet Haemocyanin.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.05% Sodium azide
Constituents: Whole serum- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human VIPR2 aa 400 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link P41587
- Purity
- Whole antiserum
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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2 product images
Western blot - Anti-VPAC2 antibody (ab28624)
All lanes: Western blot - Anti-VPAC2 antibody (ab28624) at 1/500 dilution
All lanes: PC-3 cell lysate at 30 µg
SecondaryAll lanes: Goat anti-Rabbit IgG (H+L), HRP conjugate at 1/4000 dilution
Predicted band size: 49 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VPAC2 antibody (ab28624)
ab28624 staining Human VIP Receptor 2 in human neuroendocrine cells of the small intestine by immunohistochemistry using paraffin embedded tissue.
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