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AB247142

Anti-WBSCR16 antibody

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(3 Publications)

Rabbit Polyclonal WBSCR16 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human RCC1L aa 100-250.

View Alternative Names

WBSCR16, RCC1L, RCC1-like G exchanging factor-like protein, RCC1-like protein, Williams-Beuren syndrome chromosomal region 16 protein

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WBSCR16 antibody (AB247142)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WBSCR16 antibody (AB247142)

Paraffin-embedded human kidney tissue stained for WBSCR16 using ab247142 at 1/20 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human RCC1L aa 100-250. The exact immunogen used to generate this antibody is proprietary information.

Q96I51

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/50", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion (PubMed : 28746876). Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system (PubMed : 27667664).. Isoform 1. Plays an essential role in mitochondrial ribosome biogenesis via its association with GTPases that play a role in the assembly of the large ribosome subunit.. Isoform 2. Plays an essential role in mitochondrial ribosome biogenesis via its association with GTPases that play a role in the assembly of the small ribosome subunit.
See full target information RCC1L

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 15:13811 PubMed40259011

2025

Human RCC1L is involved in the maintenance of mitochondrial nucleoids and mtDNA.

Applications

Unspecified application

Species

Unspecified reactive species

Emi Matsumoto,Taeko Sasaki,Tetsuya Higashiyama,Narie Sasaki

Cell & bioscience 11:195 PubMed34789336

2021

NME6 is a phosphotransfer-inactive, monomeric NME/NDPK family member and functions in complexes at the interface of mitochondrial inner membrane and matrix.

Applications

Unspecified application

Species

Unspecified reactive species

Bastien Proust,Martina Radić,Nikolina Škrobot Vidaček,Cécile Cottet,Stéphane Attia,Frédéric Lamarche,Lucija Ačkar,Vlatka Godinić Mikulčić,Malgorzata Tokarska-Schlattner,Helena Ćetković,Uwe Schlattner,Maja Herak Bosnar

Aging 13: PubMed33558447

2021

Combined identification of , , and as effective prognostic biomarkers for hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanyuan Zhao,Bo Yang,Dong Chen,Xiaojun Zhou,Meixi Wang,Jipin Jiang,Lai Wei,Zhishui Chen
View all publications

Product promise

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