AB93871

Anti-WDR11 antibody

Name: Anti-WDR11 antibody (ab93871) | Abcam
Brand: Abcam Limited
SKU: AB93871
Price: 535 USD
Availability: InStock
Rating: 4 (4 reviews)

(4 Reviews)

(6 Publications)

Rabbit Polyclonal WDR11 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human WDR11 aa 1150 to C-terminus.

View Alternative Names

BRWD2, KIAA1351, WDR15, WDR11, WD repeat-containing protein 11, Bromodomain and WD repeat-containing protein 2, WD repeat-containing protein 15

2 Images

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Immunoprecipitation - Anti-WDR11 antibody (AB93871)

ab93871 at 1 µg/ml detecting WDR11 in HeLa whole cell lysate by WB following IP.
Lane 1 : IP with an antibody which recognizes an upstream epitope of WDR11
Lane 2 : ab93871 at 3µg/mg of lysate
Lane 3 : control IgG.
In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded.
Detection : Chemiluminescence an with exposure time of 10 seconds

All lanes:

Immunoprecipitation - Anti-WDR11 antibody (ab93871)

Predicted band size: 137 kDa

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Western blot - Anti-WDR11 antibody (AB93871)

All lanes:

Western blot - Anti-WDR11 antibody (ab93871) at 0.04 µg/mL

Lane 1:

Hela whole cell lysate at 50 µg

Lane 2:

Hela whole cell lysate at 15 µg

Lane 3:

Hela whole cell lysate at 5 µg

Lane 4:

293T cell lysate at 50 µg

Predicted band size: 137 kDa

true

Exposure time: 3min

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IP, WB

applications

Immunogen

Synthetic Peptide within Human WDR11 aa 1150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9BZH6

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-5 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed : 29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed : 29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (PubMed : 29426865).

See full target information WDR11

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cell discovery 11:23 PubMed40097395

2025

Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jinrui Wang,Shenghui Niu,Xiao Hu,Tianxing Li,Shengduo Liu,Yingfeng Tu,Zehua Shang,Lin Zhao,Pinglong Xu,Jingwen Lin,Lu Chen,Daniel D Billadeau,Da Jia

Cell 187:4272-4288.e20 PubMed39013469

2024

The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Huaqing Deng,Guowen Jia,Ping Li,Yingying Tang,Lin Zhao,Qin Yang,Jia Zhao,Jinrui Wang,Yingfeng Tu,Xin Yong,Sitao Zhang,Xianming Mo,Daniel D Billadeau,Zhaoming Su,Da Jia

Journal of virology 96:e0182721 PubMed35020472

2022

Human Cytomegalovirus Hijacks WD Repeat Domain 11 for Virion Assembly Compartment Formation and Virion Morphogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Yang,YongXuan Yao,Han Cheng,Xian-Zhang Wang,Yue-Peng Zhou,Sheng-Nan Huang,Xuehui Ma,Hong Yang,Jinpeng Wu,Xuan Jiang,Shuang Cheng,Jin-Yan Sun,Wen-Bo Zeng,Jason Chen,Fu-Kun Zhang,Hong-Jie Shen,Jian-Yang Gu,Michael A McVoy,William J Britt,Sitang Gong,Min-Hua Luo

European journal of human genetics : EJHG 29:1663-1668 PubMed34413497

2021

Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability.

Applications

Unspecified application

Species

Unspecified reactive species

Natja Haag,Ene-Choo Tan,Matthias Begemann,Lars Buschmann,Florian Kraft,Petra Holschbach,Angeline H M Lai,Maggie Brett,Ganeshwaran H Mochida,Stephanie DiTroia,Lynn Pais,Jennifer E Neil,Muna Al-Saffar,Laila Bastaki,Christopher A Walsh,Ingo Kurth,Cordula Knopp

Nature communications 9:596 PubMed29426865

2018

The WDR11 complex facilitates the tethering of AP-1-derived vesicles.

Applications

WB, ICC/IF

Species

Unspecified reactive species, Unspecified reactive species

Paloma Navarro Negredo,James R Edgar,Paul T Manna,Robin Antrobus,Margaret S Robinson

Journal of virology 89:9841-52 PubMed26178983

2015

Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at the trans-Golgi Network To Promote Virus Replication.

Applications

Unspecified application

Species

Unspecified reactive species

Kathryne E Taylor,Karen L Mossman

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-WDR11 antibody

Immunoprecipitation - Anti-WDR11 antibody (AB93871)

Western blot - Anti-WDR11 antibody (AB93871)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise