Anti-XPNPEP1 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

XPNPEP1 plays a role in protein and peptide metabolism by processing proline-containing substrates. It does not associate with any catalytic complexes but functions autonomously to modulate peptide availability and activity. Its enzymatic activity aids in regulating peptides involved in cellular signaling and function. XPNPEP1 helps maintain homeostasis by ensuring the correct processing and degradation of proline-containing peptides which can influence numerous physiological processes.

Pathways

XPNPEP1 participates in the renin-angiotensin system (RAS) and the bradykinin degradation pathway. In the RAS XPNPEP1 modulates angiotensin molecules therefore impacting blood pressure regulation. It interacts with angiotensin-converting enzyme (ACE) within this system. In the bradykinin degradation pathway XPNPEP1 helps break down bradykinin peptides therefore preventing prolonged inflammatory responses and vascular permeability changes. Its activity is important in maintaining balance within these systems.