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AB223505

Anti-YIPF3 antibody

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(1 Publication)

Rabbit Polyclonal YIPF3 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human YIPF3 aa 1-150.

View Alternative Names

C6orf109, KLIP1, YIPF3, Protein YIPF3, Killer lineage protein 1, Natural killer cell-specific antigen KLIP1, YIP1 family member 3

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-YIPF3 antibody (AB223505)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-YIPF3 antibody (AB223505)

PC-3 (human prostate adenocarcinoma cell line) cells stained for YIPF3 (green) using ab223505 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® congugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-YIPF3 antibody (AB223505)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-YIPF3 antibody (AB223505)

Paraffin-embedded human colon cancer tissue stained for YIPF3 using ab223505 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-YIPF3 antibody (AB223505)
  • WB

Supplier Data

Western blot - Anti-YIPF3 antibody (AB223505)

All lanes:

Western blot - Anti-YIPF3 antibody (ab223505) at 1/500 dilution

Lane 1:

Mouse heart lysate

Lane 2:

Mouse liver lysate

Lane 3:

Mouse brain lysate

Lane 4:

Mouse stomach lysate

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 38 kDa

Observed band size: 39 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human YIPF3 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

Q9GZM5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

YIPF3 also known as YIP1 family member 3 is a protein with a molecular mass of approximately 41 kDa. It localizes mainly to the Golgi apparatus and endoplasmic reticulum (ER) within cells. YIPF3 is highly expressed in a variety of tissues including liver kidney and brain indicating its widespread function throughout the body. This protein belongs to the Yip1 family which is associated with membrane trafficking processes.
Biological function summary

The main role of YIPF3 involves regulation of the secretory pathway. It functions as part of a larger protein complex interacting with other members of the YIP family as well as Rab GTPases. YIPF3 contributes to the maintenance and formation of Golgi morphology ensuring proper vesicle trafficking between the ER and Golgi compartments. This activity is essential for efficient processing and transport of proteins and lipids in the cell.

Pathways

The involvement of YIPF3 can prominently be seen in the secretory and transport pathways of eukaryotic cells. It associates with the Rab GTPase pathway influencing vesicle budding and fusion essential for cellular transport mechanisms. YIPF3 works alongside Rab proteins to facilitate correct vesicular movement and signal transduction ensuring proper protein sorting and secretion.

Disruptions involving YIPF3 have connections to neurodegenerative diseases and certain cancers. Dysfunction in YIPF3 activity can lead to impaired vesicle trafficking contributing to neuron degeneration seen in neuronal disorders. Additionally alterations in YIPF3 expression levels have been observed in some oncological diseases highlighting its connection to cancer pathways. Its interplay with proteins such as Rab GTPases further illustrates the potential for broader impacts on disease development and progression.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
See full target information YIPF3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

PloS one 20:e0315922 PubMed39813259

2025

3D fluorescence staining and confocal imaging of low amount of intestinal organoids (enteroids): Protocol accessible to all.

Applications

Unspecified application

Species

Unspecified reactive species

Ami Gloria Toulehohoun,Caroline Bouzin,Aurélie Daumerie,Luca Maccioni,Peter Stärkel
View all publications
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