Rabbit Polyclonal ZBTB9 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse samples. Immunogen corresponding to Synthetic Peptide within Human Zinc finger and BTB domain-containing protein 9.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human Zinc finger and BTB domain-containing protein 9. The exact immunogen used to generate this antibody is proprietary information. Database link Q96C00
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Mouse | Tested | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1.00000-2.00000 µg/mL | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 20 µg/mL | Notes - |
Target data
Function
May be involved in transcriptional regulation.
Alternative names
Zinc finger and BTB domain-containing protein 9, ZBTB9
Recommended products
Rabbit Polyclonal ZBTB9 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse samples. Immunogen corresponding to Synthetic Peptide within Human Zinc finger and BTB domain-containing protein 9.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human Zinc finger and BTB domain-containing protein 9. The exact immunogen used to generate this antibody is proprietary information. Database link Q96C00
- Purification technique
- Affinity purification Immunogen
- Specificity
ab106628 is predicted to not cross-react with other ZBTB family members
- Concentration
- Purification notes
ab106628 is purified by affinity chromatography via a peptide column.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- Up to 12 months
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
ZBTB9 also known as Zinc Finger and BTB Domain-Containing Protein 9 is a transcription factor involved in gene expression regulation. It has an approximate mass of 56 kDa. The protein contains a conserved C2H2-type zinc finger domain which allows it to bind specific DNA sequences and modulate transcription. ZBTB9 is mainly expressed in the human brain and various tissues indicating a broad role in physiological processes. This protein's activity is essential for the regulation of genes involved in numerous cellular functions.
- Biological function summary
Expertise in transcription regulation reveals ZBTB9 as a significant player. It often functions individually but can associate with other proteins to form complexes that may influence its role in transcription repression or activation. ZBTB9 interacts with different transcriptional co-repressors and co-activators to control the expression of target genes involved in cell cycle regulation apoptosis and differentiation. This precise gene regulation allows the cell to respond to various developmental and external stimuli maintaining cellular homeostasis.
- Pathways
Current studies connect ZBTB9 to important transcriptional pathways like the Wnt signaling path and the cell cycle control path. In the Wnt pathway ZBTB9 interacts with proteins such as β-catenin to modulate gene expression important for cell proliferation and differentiation. In the cell cycle path it may interact with key regulators like cyclins and CDKs to influence cell division ensuring proper cell cycle progression and arrest when necessary. These interactions place ZBTB9 as a pivotal mediator in pathways affecting cellular growth and development.
- Associated diseases and disorders
Understanding the connection of ZBTB9 to pathological conditions can provide insights into its clinical significance. ZBTB9 has shown relevance in neurodegenerative diseases particularly Alzheimer's disease due to its expression in the brain and association with neural cell functions. It also appears in studies related to cancer biology with connections to proteins such as p53 indicating a role in tumorigenesis processes like cell cycle dysregulation and apoptosis resistance. These associations suggest that ZBTB9 could be a potential target for therapeutic strategies in diseases where its pathways and interactions are disrupted.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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3 product images
Immunocytochemistry/ Immunofluorescence - Anti-ZBTB9 antibody (ab106628)
Immunofluorescence of ZBTB9 in mouse heart tissue with ab106628 at 20 ug/mL.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZBTB9 antibody (ab106628)
Immunohistochemistry of ZBTB9 in mouse heart tissue with ab106628 at 2.5 μg/mL.
Western blot - Anti-ZBTB9 antibody (ab106628)
All lanes: Western blot - Anti-ZBTB9 antibody (ab106628) at 1 µg/mL
Lane 1: Mouse heart tissue lysate at 15 µg
Lane 2: Mouse heart tissue lysate at 15 µg with blocking peptide
Predicted band size: 50 kDa
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