Anti-ZC3H10 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The protein ZC3H10 also known as Zinc Finger CCCH-Type Containing 10 has a molecular mass of approximately 92 kDa. It possesses three tandem CCCH-type zinc finger motifs granting it the ability to bind RNA. This feature allows ZC3H10 to perform roles in post-transcriptional regulation. You can find its expression in various tissues with high expression levels in the heart and skeletal muscle indicating its importance in these tissues.

Biological function summary

The protein interacts with cellular processes involving RNA stability and degradation. ZC3H10 works as a component of ribonucleoprotein complexes suggesting it participates in the maturation of RNA processes. This involvement hints at a regulatory function impacting RNA dynamics—specifically the transition from synthesis to decay within cells.

Pathways

Its activity links to the regulation of mRNA processing pathways and mRNA decay pathways. ZC3H10 interacts with related proteins like CNOT7 influencing the deadenylation process an important step for mRNA degradation. These pathways ensure controlled mRNA levels allowing for precise gene expression which is essential for maintaining cellular homeostasis.

Associated diseases and disorders

ZC3H10 displays connections with certain cancers and muscular disorders. Changes in ZC3H10 levels or function can contribute to tumorigenesis since it impacts mRNA stability and decay processes often dysregulated in cancer cells. Furthermore its expression link with skeletal muscle indicates potential involvement in muscular dystrophies. Through its interaction with proteins like SMAD4 in muscle tissue ZC3H10 could influence pathways that might become impaired in these disorders.