Rabbit Polyclonal ZFP64 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZFP64 aa 450-600.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human ZFP64 aa 450-600. The exact immunogen used to generate this antibody is proprietary information. Database link Q9NTW7
Reactivity data
Select an application| IHC-P | ICC/IF | |
|---|---|---|
| Human | Tested | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/20.00000 - 1/50.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 0.25000-2.00000 µg/mL | Notes - |
Associated Products
Select an associated product type
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Target data
Function
May be involved in the regulation of mesenchymal cell differentiation through transactivation of NOTCH1 target genes.
Alternative names
ZNF338, ZFP64, Zinc finger protein 64, Zfp-64, Zinc finger protein 338
Recommended products
Rabbit Polyclonal ZFP64 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZFP64 aa 450-600.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human ZFP64 aa 450-600. The exact immunogen used to generate this antibody is proprietary information. Database link Q9NTW7
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
ZFP64 also known as Zinc Finger Protein 64 acts as a transcription factor with a molecular mass of approximately 71 kDa. This protein contains multiple zinc finger domains and is highly expressed in various tissues including the brain liver and lymphoid tissues. ZFP64 regulates the transcription of target genes by binding to specific DNA sequences influencing gene expression patterns in cells.
- Biological function summary
Zinc Finger Protein 64 is involved in critical cellular processes such as cell differentiation and proliferation. It contributes to gene regulation in the context of chromatin remodeling complexes but not as a direct component. ZFP64 plays significant roles in immune response modulation and neural development affecting both protein coding and non-coding regions of the genome. Research has shown its involvement in T-cell regulation and neuronal lineage determination.
- Pathways
Zinc Finger Protein 64 plays an important role in the Wnt signaling pathway and the NF-kB signaling pathway. In the Wnt signaling pathway ZFP64 interacts with other proteins to control cellular processes such as growth and migration. In the NF-kB pathway ZFP64 cooperates with other transcription factors to regulate inflammatory responses and immune system activation interacting with proteins such as IKK and RelA in the process.
- Associated diseases and disorders
Research connects Zinc Finger Protein 64 to the development of autoimmune diseases and certain types of cancer such as leukemia. Alterations in ZFP64 expression or mutations may impact the regulation of immune genes leading to uncontrolled immune responses or tumor progression. The protein is also linked to aberrations in the activity of MYC in cancerous conditions influencing the cell cycle and apoptosis pathways.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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2 product images
Immunocytochemistry/ Immunofluorescence - Anti-ZFP64 antibody (ab204610)
Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized U-2 OS cells labeling ZFP64 with ab204610 at 4μg/ml (green).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZFP64 antibody (ab204610)
Immunohistochemical analysis of paraffin-embedded Human urinary bladder tissue labeling ZFP64 with ab204610 at 1/20 dilution.
Downloads
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