AB85761

Anti-Zinc finger protein 276 antibody

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(1 Publication)

Rabbit Polyclonal Zinc finger protein 276 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF276 aa 550 to C-terminus.

View Alternative Names

CENP-Z, ZFP276, ZNF477, ZNF276, Zinc finger protein 276, Zfp-276, Zinc finger protein 477

1 Images

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Western blot - Anti-Zinc finger protein 276 antibody (AB85761)

All lanes:

Western blot - Anti-Zinc finger protein 276 antibody (ab85761) at 1 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

HeLa whole cell lysate at 5 µg

Lane 4:

293T whole cell lysate at 50 µg

Predicted band size: 60 kDa

Observed band size: 67 kDa,72 kDa

false

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human ZNF276 aa 550 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q8N554

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab85761 was affinity purified using an epitope specific to Zinc finger protein 276 immobilized on solid support.

Storage buffer

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Zinc finger protein 276 also known as ZNF276 is a transcription factor characterized by its zinc finger motifs which facilitate its binding to DNA. It weighs approximately 63 kilodaltons. ZNF276 plays a role in gene regulation and its expression occurs in various tissues including the brain and heart. It localizes predominantly in the nucleus where it modulates gene expression by interacting with other molecules and compounds.

Biological function summary

Zinc finger protein 276 functions in cellular processes through regulation of transcription. It may exist as part of a larger protein complex that helps in the control of specific genes involved in development and differentiation. The protein possibly interacts with other transcription factors to influence growth-related genes but further details of its partners remain under investigation. New studies continue to clarify how ZNF276 can directly affect chromatin remodeling and gene accessibility.

Pathways

Zinc finger protein 276 acts within the context of pathways related to gene expression modulation and cell cycle regulation. It may interact within signaling pathways like Wnt signaling known for its role in embryonic development and cancer. ZNF276 has relationships with other transcriptional regulators such as TCF/LEF family proteins involved in Wnt signaling pathways providing an intersection point for transcriptional control processes.

Zinc finger protein 276 has links to certain cancers and neurodevelopmental disorders. Its abnormal expression or mutations can impact the regulation of genes involved in these conditions. ZNF276's role in gene expression control places it as a node of intersection with other proteins like C-MYC commonly dysregulated in cancers. More research is required to delineate its specific contributions to these disease mechanisms and the interactions with associated proteins.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May be involved in transcriptional regulation.

See full target information ZNF276

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of cell biology 219: PubMed32697819

2020

HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions.

Applications

Unspecified application

Species

Unspecified reactive species

Alexis Osseni,Aymeric Ravel-Chapuis,Jean-Luc Thomas,Vincent Gache,Laurent Schaeffer,Bernard J Jasmin

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Zinc finger protein 276 antibody

Western blot - Anti-Zinc finger protein 276 antibody (AB85761)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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Product promise