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AB169587

Anti-Zinc finger protein 668 antibody

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(1 Publication)

Mouse Polyclonal Zinc finger protein 668 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ZNF668.

View Alternative Names

Zinc finger protein 668, ZNF668

1 Images
Western blot - Anti-Zinc finger protein 668 antibody (AB169587)
  • WB

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Western blot - Anti-Zinc finger protein 668 antibody (AB169587)

All lanes:

Western blot - Anti-Zinc finger protein 668 antibody (ab169587) at 1 µg/mL

Lane 1:

Zinc finger protein 668-transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Predicted band size: 68 kDa

true

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ZNF668.

Q96K58

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cynomolgus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Zinc finger protein 668 also known as ZNF668 is a transcription factor that contains zinc finger domains which allow it to bind to specific DNA sequences. This protein has a mass of approximately 82 kDa. Scientists have observed its expression in various tissues often higher in certain regions of the brain and testes. ZNF668 plays a significant role in regulating gene expression by interacting directly with DNA influencing cellular processes through transcriptional regulation.
Biological function summary

Zinc finger protein 668 modulates important gene networks involved in cell proliferation and differentiation. It functions not independently but as part of a larger transcriptional complex engaging in interactions with other proteins that enable it to effectively regulate gene expression. By binding to DNA ZNF668 can activate or repress the transcription of specific target genes impacting cellular functions and maintaining homeostasis.

Pathways

Researchers place zinc finger protein 668 within the p53 signaling pathway influencing cell cycle regulation and apoptosis. The interactions of ZNF668 with p53-related proteins contribute to its role in DNA damage response and maintaining genomic stability. Another important pathway involving ZNF668 is the Wnt signaling pathway where it interacts with other pathway components to modulate cell fate determination and embryonic development processes.

Zinc finger protein 668 has connections to certain cancers including breast cancer where its dysregulation can contribute to tumorigenesis. Altered expression of ZNF668 may impact its interactions with p53 and other oncogenic proteins such as MDM2 leading to uncontrolled cell growth. Additionally abnormalities in ZNF668 activity relate to neurological disorders possibly due to its expression in the brain and roles in neural differentiation pathways.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation. May play a role in DNA repair process.
See full target information ZNF668
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell death and differentiation 30:2213-2230 PubMed37726400

2023

LncRNA BCAN-AS1 stabilizes c-Myc via N-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Guandi Wu,Jiachun Su,Lingxing Zeng,Shuang Deng,Xudong Huang,Ying Ye,Rui Li,Ruihong Bai,Lisha Zhuang,Mei Li,Quanbo Zhou,Yanfen Zheng,Junge Deng,Shaoping Zhang,Rufu Chen,Dongxin Lin,Jialiang Zhang,Jian Zheng
View all publications
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