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AB222833

Anti-ZNF2 antibody

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(1 Publication)

Rabbit Polyclonal ZNF2 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF2 aa 100-300.

View Alternative Names

ZNF661, ZNF2, Zinc finger protein 2, Zinc finger protein 2.2, Zinc finger protein 661

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF2 antibody (AB222833)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF2 antibody (AB222833)

Paraffin-embedded human endometrial cancer tissue stained for ZNF2 using ab222833 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF2 antibody (AB222833)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF2 antibody (AB222833)

Paraffin-embedded human pancreatic cancer tissue stained for ZNF2 using ab222833 at 1/100 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human ZNF2 aa 100-300. The exact immunogen used to generate this antibody is proprietary information.

Q9BSG1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
>95%
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF2 also known as Zinc Finger Protein 2 or KOX1 is a protein encoded by the ZNF2 gene in humans. This protein belongs to the family of zinc finger proteins which play a role in regulating gene expression through DNA binding. ZNF2 has a molecular mass of approximately 66 kDa. It is expressed in several tissues including the brain liver and kidney. Its expression levels can vary depending on the type of tissue indicating a diverse role in different physiological contexts.
Biological function summary

Researchers recognize ZNF2 as a transcription factor that binds to specific DNA sequences to regulate transcription. The protein likely participates in forming a complex with other transcription factors and co-regulators modulating the expression of genes involved in cellular proliferation differentiation and apoptosis. This activity implies its significance in maintaining cellular homeostasis and influencing cell fate decisions.

Pathways

The function of ZNF2 integrates into gene expression and signaling pathways. It associates with pathways involving transcription regulation such as the Wnt signaling pathway which is pivotal in development and cellular differentiation. ZNF2 may interact with other signaling proteins such as β-catenin contributing to the pathway's ability to transduce signals from the cellular environment to the nucleus and modify the transcription of target genes.

The role of ZNF2 links to various cancer types including liver and brain cancers. Alterations in ZNF2 expression or function may be a factor in oncogenesis and cancer progression. Through these disease processes ZNF2 may interact with tumor suppressor proteins like p53 which is important in preventing cancer formation. Understanding the relationship between ZNF2 and these disorders can offer insights into therapeutic strategies targeting this protein or its pathways.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of biological sciences 16:2835-2852 PubMed33061800

2020

Rictor promotes cell migration and actin polymerization through regulating ABLIM1 phosphorylation in Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Dong,Mei Feng,Hui Yang,Hengkang Liu,Hua Guo,Xianshu Gao,Yucun Liu,Rong Liu,Ning Zhang,Ruibing Chen,Ruirui Kong
View all publications
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Product promise

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