AB180121

Anti-ZNF24 antibody [EPR13975]

RabMAb
Recombinant
What is this?

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(2 Publications)

Rabbit Recombinant Monoclonal ZNF24 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 2 publications.

View Alternative Names

KOX17, ZNF191, ZSCAN3, ZNF24, Zinc finger protein 24, Retinoic acid suppression protein A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein KOX17, RSG-A

2 Images

Flow Cytometry (Intracellular) - Anti-ZNF24 antibody [EPR13975] (AB180121)

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-ZNF24 antibody [EPR13975] (AB180121)

Intracellular flow cytometric analysis of HeLa cells (paraformaldehyde-fixed, 2%) labeling ZNF24with ab180121 at 1/10 dilution (red) or a rabbit IgG (negative) (green), followed by secondary Goat anti rabbit IgG (FITC) at 1/75 dilution. Isotype control Rabbit IgG.

Supplier Data

Western blot - Anti-ZNF24 antibody [EPR13975] (AB180121)

All lanes:

Western blot - Anti-ZNF24 antibody [EPR13975] (ab180121) at 1/10000 dilution

Lane 1:

Jurkat cell lysate at 20 µg

Lane 2:

HeLa cell lysate at 20 µg

Lane 3:

293 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 42 kDa

Observed band size: 50 kDa

false

Carrier free

Anti-ZNF24 antibody [EPR13975] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13975

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, Flow Cyt (Intra)

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/10", "FlowCytIntra-species-notes": "<p><a href='/en-us/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.</p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Conditional Ambient

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF24 also known as zinc finger protein 191 is a transcription factor with a molecular weight of approximately 55 kDa. It functions by binding to specific DNA sequences through its zinc finger domains thereby influencing the transcription of genes. The expression of ZNF24 occurs in various tissues including the liver lung and brain suggesting its role in multiple cellular processes. This protein plays a significant role in gene regulation due to its ability to bind DNA and modulate the expression of specific genes.

Biological function summary

Zinc finger protein 191 regulates cell proliferation differentiation and development. It does not typically form part of a larger protein complex acting mostly as a solitary transcription factor. By influencing the expression of genes involved in cell cycle progression and differentiation ZNF24 contributes to maintaining cellular homeostasis. Alterations in its expression can affect these biological processes leading to various cellular dysfunctions and abnormalities.

Pathways

Zinc finger protein 191 plays a role in the Wnt signaling and cell cycle pathways. In the Wnt signaling pathway ZNF24 modulates the transcription of target genes that are essential for cell proliferation and differentiation. In the cell cycle pathway it interacts directly with proteins such as cyclins and cyclin-dependent kinases which are important for the control of cell cycle transitions. This involvement in key signaling pathways highlights its importance in regulating cellular growth and division.

Zinc finger protein 191 has been linked to cancer and neurodegenerative diseases. In cancer ZNF24 dysregulation can lead to uncontrolled cell proliferation as it interacts with proteins like β-catenin within the Wnt signaling pathway. In neurodegenerative diseases the altered expression of ZNF24 affects neuronal cell function as it potentially interacts with amyloid precursor proteins disrupting normal neuronal processes. These connections indicate the potential implications of ZNF24 in both oncogenesis and neurodegenerative conditions.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.

See full target information ZNF24

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell death & disease 16:334 PubMed40274778

2025

The deubiquitinase YOD1 suppresses tumor progression by stabilizing ZNF24 in clear cell renal carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Liu,Ying Lu,Runye Zhu,Ping Xi,Zhihao Yang,Zhipeng Zhang,Yunbing Xiong,Yifu Liu,Qiqi Zhu,Ting Sun,Wenjie Xie,Binbin Gong

Oncotarget 8:63026-63037 PubMed28968968

2017

Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.

Applications

Species

Unspecified reactive species

Ziyu Le,Xiaoshuang Niu,Ying Chen,Xiaomin Ou,Guoqi Zhao,Qi Liu,Wenzhi Tu,Chaosu Hu,Lin Kong,Yong Liu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-ZNF24 antibody [EPR13975]

Flow Cytometry (Intracellular) - Anti-ZNF24 antibody [EPR13975] (AB180121)

Western blot - Anti-ZNF24 antibody [EPR13975] (AB180121)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Proteins & Peptides

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

Product promise