Rabbit Polyclonal ZNF295 antibody. N-terminal. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZBTB21.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Liquid
Polyclonal
WB | |
---|---|
Human | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
Select an associated product type
KIAA1227, ZNF295, ZBTB21, Zinc finger and BTB domain-containing protein 21, Zinc finger protein 295
Rabbit Polyclonal ZNF295 antibody. N-terminal. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZBTB21.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Liquid
Polyclonal
Affinity purification Immunogen
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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This supplementary information is collated from multiple sources and compiled automatically.
ZNF295 also known as zinc finger protein 295 is a transcription factor that contains a zinc finger domain enabling interaction with DNA. It has an approximate mass of 115 kDa. ZNF295 is expressed in various tissues including brain liver and heart where it may control gene expression by binding specific DNA sequences. Its role in gene regulation indicates a significant impact on cellular processes influencing development and cellular differentiation.
This transcription factor interacts with other proteins to modulate gene expression by forming complexes. It participates in regulating genes involved in cell growth and development. The zinc finger domain allows ZNF295 to bind DNA acting as a switch to activate or repress transcription. Through its activity it contributes to maintaining normal cellular function and responding to environmental changes which is essential for organismal homeostasis.
ZNF295 plays roles in key signaling pathways such as the cell growth and differentiation pathways. It interacts with other transcription factors and proteins including members of the p53 family which are important in managing cell cycle and apoptosis. This involvement positions ZNF295 as a potential regulator of various cellular activities modulating the balance between cell survival and programmed cell death.
Mutations and altered expression of ZNF295 have connections to cancer and neurodevelopmental disorders. Disruptions in its function can lead to abnormal cell proliferation and differentiation conditions often observed in cancers. In neurodevelopmental disorders ZNF295 may play a role alongside proteins such as MECP2 in brain development anomalies. Understanding its contributions to these diseases allows for the exploration of targeted therapies that may modify its activity.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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7.5% SDS-PAGE gel.
All lanes: Western blot - Anti-ZNF295 antibody - N-terminal (ab228955) at 1/2000 dilution
All lanes: HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 30 µg
Predicted band size: 119 kDa
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