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Rabbit Polyclonal ZNF307 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZKSCAN4 aa 50-300.

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Images

Western blot - Anti-ZNF307 antibody (AB154365), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human ZKSCAN4 aa 50-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q969J2

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested

Tested
Tested

Species

Human

Dilution info

1/500.00000 - 1/3000.00000

Notes

-

Target data

Function

May be involved in the transcriptional activation of MDM2 and EP300 genes.

Alternative names

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Rabbit Polyclonal ZNF307 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human ZKSCAN4 aa 50-300.

Alternative names

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human ZKSCAN4 aa 50-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q969J2
Purification technique

Affinity purification Immunogen

Concentration
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Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

Activity summary

ZNF307 also known as Zinc Finger Protein 307 is a transcription factor with a molecular mass of about 69 kDa. It functions mechanically as a DNA-binding protein regulating gene expression by modulating the transcriptional activity of various genes. ZNF307 is mainly expressed in the nucleus and its expression has been detected in multiple human tissues including the liver kidney and placenta. This protein contains multiple zinc finger motifs that facilitate specific binding to DNA sequences making it important for transcriptional regulation.

Biological function summary

ZNF307 influences cellular processes by acting as a regulatory factor that modulates gene expression. It is not typically part of a larger protein complex but rather functions independently to exert its regulatory effects. ZNF307 controls genes associated with cell cycle progression and differentiation impacting important cellular activities and growth-related behaviors. The direct interaction of ZNF307 with DNA elements highlights its role in influencing the transcriptional landscape of the cell.

Pathways

ZNF307 plays a significant role in transcriptional regulation and cell cycle pathways. It affects these pathways by interacting with proteins such as p53 a well-known tumor suppressor and other regulatory proteins that control the cell cycle. The relationship of ZNF307 within these pathways involves a balancing act between cell proliferation and differentiation where its functional dynamics can sway cellular outcomes based on environmental and intrinsic signals.

Associated diseases and disorders

ZNF307 has potential connections to cancer and metabolic syndromes. Its interactions with proteins such as p53 suggest a role in tumorigenesis as alterations in ZNF307 expression or function may influence the cell cycle control and apoptosis. Additionally ZNF307's influence on metabolism-related pathways could place it in the context of metabolic disorders as it may affect the regulation of genes involved in metabolic homeostasis. Overall the study of ZNF307 may reveal insights into its link to disease progression and offer avenues for therapeutic intervention.

Product promise

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1 product image

  • Western blot - Anti-ZNF307 antibody (ab154365), expandable thumbnail

    Western blot - Anti-ZNF307 antibody (ab154365)

    7.5% SDS PAGE

    All lanes: Western blot - Anti-ZNF307 antibody (ab154365) at 1/1000 dilution

    All lanes: Jurkat whole cell lysate at 30 µg

    Predicted band size: 62 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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