Anti-ZNF307 antibody

Supplementary info

Activity summary

ZNF307 also known as Zinc Finger Protein 307 is a transcription factor with a molecular mass of about 69 kDa. It functions mechanically as a DNA-binding protein regulating gene expression by modulating the transcriptional activity of various genes. ZNF307 is mainly expressed in the nucleus and its expression has been detected in multiple human tissues including the liver kidney and placenta. This protein contains multiple zinc finger motifs that facilitate specific binding to DNA sequences making it important for transcriptional regulation.

Biological function summary

ZNF307 influences cellular processes by acting as a regulatory factor that modulates gene expression. It is not typically part of a larger protein complex but rather functions independently to exert its regulatory effects. ZNF307 controls genes associated with cell cycle progression and differentiation impacting important cellular activities and growth-related behaviors. The direct interaction of ZNF307 with DNA elements highlights its role in influencing the transcriptional landscape of the cell.

Pathways

ZNF307 plays a significant role in transcriptional regulation and cell cycle pathways. It affects these pathways by interacting with proteins such as p53 a well-known tumor suppressor and other regulatory proteins that control the cell cycle. The relationship of ZNF307 within these pathways involves a balancing act between cell proliferation and differentiation where its functional dynamics can sway cellular outcomes based on environmental and intrinsic signals.

Associated diseases and disorders

ZNF307 has potential connections to cancer and metabolic syndromes. Its interactions with proteins such as p53 suggest a role in tumorigenesis as alterations in ZNF307 expression or function may influence the cell cycle control and apoptosis. Additionally ZNF307's influence on metabolism-related pathways could place it in the context of metabolic disorders as it may affect the regulation of genes involved in metabolic homeostasis. Overall the study of ZNF307 may reveal insights into its link to disease progression and offer avenues for therapeutic intervention.