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AB127196

Anti-ZNF31 antibody

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(1 Publication)

Rabbit Polyclonal ZNF31 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ZSCAN20 aa 300-550.

View Alternative Names

KOX29, ZNF31, ZNF360, ZSCAN20, Zinc finger and SCAN domain-containing protein 20, Zinc finger protein 31, Zinc finger protein 360, Zinc finger protein KOX29

1 Images
Western blot - Anti-ZNF31 antibody (AB127196)
  • WB

Unknown

Western blot - Anti-ZNF31 antibody (AB127196)

7.5% SDS-PAGE

All lanes:

Western blot - Anti-ZNF31 antibody (ab127196) at 1/5000 dilution

Lane 1:

Jurkat whole cell lysate at 30 µg

Lane 2:

Raji whole cell lysate at 30 µg

Lane 3:

K562 whole cell lysate at 30 µg

Predicted band size: 118 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human ZSCAN20 aa 300-550. The exact immunogen used to generate this antibody is proprietary information.

P17040

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF31 also known as zinc finger protein 31 functions mechanically as a gene transcription regulator. It belongs to a family of proteins containing zinc finger motifs key to binding DNA and influencing gene expression. ZNF31 has a molecular mass of approximately 198 kDa and can be found predominantly in the nucleus of cells. It is expressed in various tissues including the brain and liver where it likely participates in essential regulatory roles.
Biological function summary

This target plays a significant role in controlling gene expression by binding specific DNA sequences. ZNF31 acts as a transcription factor; it can either activate or repress the expression of target genes. Evidence suggests that ZNF31 is part of a transcriptional complex that may involve other zinc finger proteins. These interactions enable ZNF31 to modulate cellular processes like proliferation and differentiation highlighting its regulatory capacity in cellular biology.

Pathways

Researchers have identified ZNF31 as a contributor to processes within the cell cycle and apoptosis pathways. In the cell cycle ZNF31 interacts with other proteins to influence cell proliferation and division. It has a relationship with p53 an important protein that regulates the cell cycle and promotes apoptosis if DNA damage is detected. The regulation of these pathways highlights the involvement of ZNF31 in maintaining normal cellular function and preventing abnormal cell growth.

ZNF31 has been associated with various types of cancer where dysregulation might result in aberrant cell proliferation. The interaction of ZNF31 with oncogenes or tumor suppressor proteins like p53 suggests its role in either promoting or inhibiting tumor growth depending on the context. Additionally there is ongoing research studying its involvement in neurological disorders given its expression in the brain. These potential links offer insights into how ZNF31 dysfunction may contribute to the development of these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZSCAN20
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 32: PubMed40709397

2025

Pan‑cancer analysis of the carcinogenic role of WSB2 in human tumors.

Applications

Unspecified application

Species

Unspecified reactive species

Yingzi Deng,Yifei Li,Ruobing Li,Xiaohui Guo,Yan Liu,Shuqing Wang,Juan Zhang,Mi Li,Lina Zhao,Haifeng Cai,Yunfeng Zhang,Fen Hu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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