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AB127712

Anti-ZNF334 antibody

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(2 Publications)

Rabbit Polyclonal ZNF334 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF334 aa 50-350.

View Alternative Names

Zinc finger protein 334, ZNF334

1 Images
Western blot - Anti-ZNF334 antibody (AB127712)
  • WB

Unknown

Western blot - Anti-ZNF334 antibody (AB127712)

7.5% SDS PAGE

All lanes:

Western blot - Anti-ZNF334 antibody (ab127712) at 1/1000 dilution

All lanes:

NT2D1 whole cell lysate at 30 µg

Predicted band size: 80 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human ZNF334 aa 50-350. The exact immunogen used to generate this antibody is proprietary information.

Q9HCZ1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF334 also known as Zinc Finger Protein 334 functions as a transcription factor which means it binds to specific DNA sequences to regulate the expression of certain genes. The protein weighs approximately 57.7 kDa. You can find ZNF334 expression in various tissues most noticeably in the brain and immune cells. Its zinc finger domains contribute to its role in DNA binding influencing transcriptional activity.
Biological function summary

The protein operates within the nucleus and interacts with DNA to modulate gene expression. It forms part of a larger complex with other transcription factors enhancing or repressing transcription of target genes. This regulation plays a role in cell differentiation and development. Researchers continue studying specific genes regulated by ZNF334 to better understand its extensive biological reach.

Pathways

ZNF334 influences several important cellular processes. It takes part in signal transduction by interacting with pathways like the Notch signaling pathway which is critical for cell fate determination. Additionally it associates with the Wnt signaling pathway which impacts cell proliferation and differentiation. ZNF334 may influence these pathways by interacting with related proteins including CSL (CBF1/Su(H)/LAG-1) and Dishevelled pivotal elements in Notch and Wnt signaling respectively.

Researchers have identified ZNF334's potential involvement in neurodevelopmental disorders and autoimmune diseases. Its dysregulation may contribute to conditions like autism spectrum disorder by altering normal brain development processes. In autoimmune diseases such as systemic lupus erythematosus (SLE) ZNF334 may influence disease susceptibility through pathways involving cytokines and immune cell function. Interactions with proteins like STAT1 and STAT3 suggest ZNF334 might affect immune responses and inflammation relevant to these disorders.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF334
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Acta biochimica et biophysica Sinica 57:1106-1114 PubMed40109092

2025

METTL3-mediated m A modification of pri-miRNA-31 promotes hypertrophic scar progression.

Applications

Unspecified application

Species

Unspecified reactive species

Qirui Wang,Jialin Hou,Siyi Zeng,Xue Wang,Yimin Liang,Renpeng Zhou

Cell death & disease 13:446 PubMed35534462

2022

DNA hypermethylation modification promotes the development of hepatocellular carcinoma by depressing the tumor suppressor gene ZNF334.

Applications

Unspecified application

Species

Unspecified reactive species

Dapeng Sun,Xiaojie Gan,Lei Liu,Yuan Yang,Dongyang Ding,Wen Li,Junyao Jiang,Wenbin Ding,Linghao Zhao,Guojun Hou,Jian Yu,Jie Wang,Fu Yang,Shengxian Yuan,Weiping Zhou
View all publications
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Product promise

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