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AB219957

Anti-ZNF367 antibody

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(1 Publication)

Rabbit Polyclonal ZNF367 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF367 aa 200-350.

View Alternative Names

ZFF29, ZNF367, Zinc finger protein 367, C2H2 zinc finger protein ZFF29

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-ZNF367 antibody (AB219957)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ZNF367 antibody (AB219957)

Immunofluorescent analysis of PFA fixed, Triton X-100 permeabilized U-251 MG cells labeling ZNF367 with ab219957 at 4 μg/ml (green).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human ZNF367 aa 200-350. The exact immunogen used to generate this antibody is proprietary information.

Q7RTV3

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF367 also known as zinc finger protein 367 or ZCWCC1 is a protein that acts in transcriptional regulation. It contains multiple zinc finger domains which enable it to bind to DNA and influence gene expression. ZNF367 has a mass of approximately 34 kDa. Researchers have detected its expression primarily in the nucleus of various cell types suggesting its widespread role across different tissues.
Biological function summary

ZNF367 plays an important role in the regulation of cell cycle and maintenance of cellular proliferation. It does not form part of any known larger protein complex but influences the transcription of several genes associated with cell division. Through its activity ZNF367 supports processes such as tumorigenesis and embryonic development where precise control of cell proliferation is critical.

Pathways

The action of ZNF367 involves significant interactions within the cell cycle regulation and differentiation pathways. It frequently associates with the p53 signaling pathway which controls cell cycle arrest and apoptosis. ZNF367 interacts with proteins like MDM2 an E3 ubiquitin-protein ligase to modulate cell cycle dynamics and survival balancing cell growth with genetic integrity.

ZNF367 has notable implications in cancer particularly in breast and ovarian cancers. Its dysregulation leads to unchecked cell proliferation contributing to tumor growth and progression. ZNF367 is connected to ERBB2 also known as HER2 frequently overexpressed in certain breast cancers indicating its potential involvement in oncogenic pathways. Furthermore potential links to neurodevelopmental disorders highlight its role in neuron differentiation and brain function although these connections require further study to fully understand the mechanisms involved.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes.
See full target information ZNF367
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International archives of allergy and immunology 184:471-480 PubMed36702106

2023

RBCK1 Overexpression Attenuates Inflammation and Mobility of Derp1-Induced Nasal Mucosal Cells by Downregulating NLRP3.

Applications

Unspecified application

Species

Unspecified reactive species

Jingwei Du,Lijuan Peng,Jun Feng,Tao Zhang
View all publications
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