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AB243700

Anti-ZNF480 antibody

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(1 Publication)

Rabbit Polyclonal ZNF480 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF480 aa 100-200.

View Alternative Names

Zinc finger protein 480, ZNF480

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF480 antibody (AB243700)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF480 antibody (AB243700)

Formalin-fixed, paraffin-embedded human colon tissue stained for ZNF480 using ab243700 at 1/200 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-ZNF480 antibody (AB243700)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ZNF480 antibody (AB243700)

PFA-fixed, Triton X-100 permeabilized U-251 MG (human brain glioma cell line) cells labeling ZNF480 (Green) using ab243700 at 4 μg/mL in ICC/IF analysis.

Western blot - Anti-ZNF480 antibody (AB243700)
  • WB

Supplier Data

Western blot - Anti-ZNF480 antibody (AB243700)

All lanes:

Western blot - Anti-ZNF480 antibody (ab243700) at 0.4 µg/mL

Lane 1:

RT4 (Human urinary bladder cancer cell line) whole cell lysate

Lane 2:

U-251 MG (human brain glioma cell line) whole cell lysate

Predicted band size: 62 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human ZNF480 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

Q8WV37

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF480 also known as Zinc Finger Protein 480 is a transcription factor that works through binding to specific DNA sequences. It consists of multiple C2H2-type zinc finger motifs. The mass of ZNF480 is approximately 86 kDa. This protein is expressed in various tissues including the liver kidney and heart suggesting its involvement in diverse physiological processes.
Biological function summary

ZNF480 regulates transcription by acting as a modulator of gene expression. It interacts with DNA to influence the transcriptional activity also indicating a potential role in chromatin remodeling. ZNF480 might be part of larger protein complexes that manage transcription processes. Through its function ZNF480 assists in cellular differentiation and proliferation impacting cell fate decisions.

Pathways

ZNF480 influences gene regulation networks involved in cell growth and differentiation. It is connected with the Notch signaling pathway which is important for many developmental processes. ZNF480 might interact with other proteins like RBPJ an integral component of the Notch pathway to execute its regulatory roles.

Researchers have linked ZNF480 to certain cancers such as breast cancer where it might affect tumor cell proliferation. They have also associated ZNF480 with neurological disorders potentially through disrupted transcriptional regulation involving other proteins like REST which is important in neuronal gene expression modulation. Understanding ZNF480's involvement in these diseases could provide targets for therapeutic interventions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in transcriptional regulation as an activator.
See full target information ZNF480
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 15:9250 PubMed40102459

2025

Identification of methionine metabolism related prognostic model and tumor suppressive functions of BHMT in hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Wenli Liu,Kaiheng Hu,Yaqing Fu,Tianmin Zhou,Qingmei Zhong,Wu Wang,Yang Gui,Ping Zhang,Di Yao,Xiaohong Yang,Weifeng Zhu,Zhuoqi Liu,Daya Luo,Yingqun Xiao
View all publications
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Product promise

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