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AB117784

Anti-ZNF507 antibody

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(1 Publication)

Rabbit Polyclonal ZNF507 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF507 aa 1-50.

View Alternative Names

KIAA1084, ZNF507, Zinc finger protein 507

2 Images
Immunoprecipitation - Anti-ZNF507 antibody (AB117784)
  • IP

Unknown

Immunoprecipitation - Anti-ZNF507 antibody (AB117784)

Detection of ZNF507 by Western Blot of Immunprecipitate.
ab117784 at 1µg/ml staining ZNF507 in 293T whole cell lysate immunoprecipitated using ab117784 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection : Chemiluminescence with exposure time of 30 seconds.

All lanes:

Immunoprecipitation - Anti-ZNF507 antibody (ab117784)

Predicted band size: 106 kDa

false

Western blot - Anti-ZNF507 antibody (AB117784)
  • WB

Unknown

Western blot - Anti-ZNF507 antibody (AB117784)

All lanes:

Western blot - Anti-ZNF507 antibody (ab117784) at 0.1 µg/mL

Lane 1:

293T whole cell lysates at 50 µg

Lane 2:

293T whole cell lysates at 15 µg

Lane 3:

Jurkat whole cell lysates at 50 µg

Lane 4:

HeLa whole cell lysates at 50 µg

Predicted band size: 106 kDa

true

Exposure time: 3min

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, WB

applications

Immunogen

Synthetic Peptide within Human ZNF507 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q8TCN5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Elephant": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab117784 was affinity purified using an epitope specific to ZNF507 immobilized on solid support.
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF507 also known as Zinc Finger Protein 507 is a zinc finger protein that plays a role in transcriptional regulation. It has a molecular mass of approximately 156 kDa. Zinc finger proteins like ZNF507 contain characteristic motifs that bind DNA and influence gene expression. It is expressed in various tissues with notable expression in the brain and reproductive organs suggesting a role in diverse cellular functions.
Biological function summary

ZNF507 regulates gene expression by binding to specific DNA sequences. It may function as part of larger protein complexes that either promote or suppress transcription influencing cellular processes such as development and differentiation. The presence of zinc finger domains allows it to interact with other proteins and DNA helixes facilitating its role in modulating genetic transcriptional landscapes.

Pathways

Zinc finger proteins including ZNF507 participate in critical pathways that govern cell growth and development. They are involved in the regulation of the Wnt signaling pathway which is vital for cell proliferation and embryonic development. ZNF507 may interact with other transcription factors such as β-catenin that are integral to Wnt signaling and help coordinate cellular responses to developmental cues.

Alterations in ZNF507 expression or function may link to neurodevelopmental disorders and cancers. In neurodevelopmental conditions it possibly interacts with proteins that regulate early brain development although specific partner proteins in these conditions need further investigation. In cancer aberrant ZNF507 activity might connect with molecular pathways controlling cell cycle and apoptosis suggesting its role in tumorigenesis.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF507
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 40:523-536.e6 PubMed28350986

2017

Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance.

Applications

Unspecified application

Species

Unspecified reactive species

Hiroyuki Nakajima,Kimiko Yamamoto,Sobhika Agarwala,Kenta Terai,Hajime Fukui,Shigetomo Fukuhara,Koji Ando,Takahiro Miyazaki,Yasuhiro Yokota,Etienne Schmelzer,Heinz-Georg Belting,Markus Affolter,Virginie Lecaudey,Naoki Mochizuki
View all publications
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Product promise

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