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AB228833

Anti-ZNF556 antibody

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(1 Publication)

Rabbit Polyclonal ZNF556 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF556.

View Alternative Names

Zinc finger protein 556, ZNF556

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-ZNF556 antibody (AB228833)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ZNF556 antibody (AB228833)

4% paraformaldehyde-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for ZNF556 (green) using ab228833 at 1/500 dilution in ICC/IF.

Blue : Hoechst 33342 staining.

Western blot - Anti-ZNF556 antibody (AB228833)
  • WB

Supplier Data

Western blot - Anti-ZNF556 antibody (AB228833)

10% SDS-PAGE gel.

All lanes:

Western blot - Anti-ZNF556 antibody (ab228833) at 1/1000 dilution

All lanes:

RD whole cell extract at 30 µg

Predicted band size: 52 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human ZNF556. The exact immunogen used to generate this antibody is proprietary information.

Q9HAH1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF556 also known as Zinc Finger Protein 556 is a protein characterized by the presence of C2H2-type zinc finger motifs. It has a molecular mass of approximately 76 kDa. Mechanically ZNF556 plays a role in DNA binding and transcriptional regulation. It can bind to specific DNA sequences through its zinc finger domains which function as transcription factors. ZNF556 is expressed in several tissues including brain and liver indicating its potential role in various physiological processes.
Biological function summary

The activity of ZNF556 involves modulation of gene expression and its participation in regulatory networks governing cell growth and differentiation. It functions within a larger complex involving other zinc finger proteins contributing to the regulation of target gene promoters. This interaction emphasizes its importance in maintaining normal cellular processes influencing the expression of genes critical for cell cycle progression and cellular response to external stimuli.

Pathways

ZNF556 is integrated into the MAPK signaling pathway which is significant for its role in cell proliferation and stress response. It also participates in the Wnt signaling pathway influencing cell fate determination and development. Through these pathways ZNF556 interacts with proteins such as MAPK1 and beta-catenin which further illustrates its involvement in cascades that govern cellular homeostasis and development.

ZNF556 has been implicated in certain neurodegenerative diseases such as Alzheimer’s disease due to its expression in brain tissues and its role in transcription regulation. It also relates to liver cancer possibly through dysregulation of the cell cycle and proliferation pathways. In these contexts ZNF556 connects with proteins like tau in Alzheimer’s disease and p53 in liver cancer which are important in understanding the molecular mechanisms underlying these conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF556
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cellular oncology (Dordrecht) 45:355-365 PubMed35579750

2022

Bioactive peptide inhibits acute myeloid leukemia cell proliferation by downregulating ALKBH5-mediated mA demethylation of EIF4EBP1 and MLST8 mRNA.

Applications

Unspecified application

Species

Unspecified reactive species

Le Zhang,Xiulan Su
View all publications
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Product promise

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