Anti-ZNF587 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

ZNF587 also known as Zinc Finger Protein 587 acts as a transcription factor that binds to DNA to regulate gene expression. This protein contains C2H2-type zinc finger motifs which help it attach to specific DNA sequences. Its exact molecular mass remains not well-documented but like many zinc finger proteins it exists within the range typical for such transcription factors. ZNF587 expression occurs mainly in tissues of the reproductive system with notable presence in testis and ovary which indicates its role related to reproductive biological processes.

Biological function summary

Zinc finger proteins like ZNF587 play a role in transcriptional regulation by modulating the activity of other genes. ZNF587 is not known to form part of a larger protein complex but it interacts with different transcriptional machinery components to influence gene expression patterns. Its ability to bind to specific DNA regions makes it an essential regulator in maintaining normal cellular functions and possibly developmental processes related to its expression profile in reproductive tissues.

Pathways

Zinc finger proteins such as ZNF587 contribute to the intricate network of gene expression regulation part-taking in pathways such as the Wnt signaling pathway. Within this pathway ZNF587 regulates genes that control cell growth movement and differentiation working alongside proteins like β-catenin which also influences transcription by binding to DNA. This interaction highlights ZNF587's role in key signaling networks that dictate important cellular decisions and developmental cues.

Associated diseases and disorders

Research indicates connections between ZNF587 and certain reproductive system diseases including testicular cancer and polycystic ovary syndrome (PCOS). In testicular cancer altered expression of ZNF587 and its interactions with other zinc finger proteins may contribute to the pathogenesis. For PCOS ZNF587's role in reproductive tissue suggests a possible impact on the gene networks disrupted in this disorder potentially involving proteins like FSHR that regulate ovary function. Therefore understanding ZNF587 function can illuminate pathways that lead to reproductive health issues.