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AB237811

Anti-ZNF695 antibody

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(1 Publication)

Rabbit Polyclonal ZNF695 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Zinc finger protein 695.

View Alternative Names

Zinc finger protein 695, Zinc finger protein SBZF3, ZNF695

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)

Paraffin-embedded human bladder cancer tissue stained for ZNF695 using ab237811 at 1/100 dilution in imunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-ZNF695 antibody (AB237811)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ZNF695 antibody (AB237811)

HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for ZNF695 (green) using ab237811 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF695 antibody (AB237811)

Paraffin-embedded human cervical cancer tissue stained for ZNF695 using ab237811 at 1/100 dilution in imunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Full Length Protein corresponding to Human Zinc finger protein 695.

Q8IW36

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity greater than 95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF695 also known as Zinc Finger Protein 695 has a mechanical role in DNA binding and transcriptional regulation. Its molecular weight is approximately 60 kDa. Scientists observe the expression of ZNF695 in various tissues with higher levels noted in certain tumor cells. Known for its zinc finger domains ZNF695 interacts directly with DNA segments influencing the transcription of specific genes within the genome.
Biological function summary

Zinc Finger Protein 695 influences gene expression without being part of a larger known protein complex. It plays a role in cellular processes like cell differentiation and proliferation. By modulating transcription ZNF695 impacts cellular responses to external signals contributing to the regulation of important physiological functions. Its activity can affect a range of cellular states reflecting the capability of transcription factors to mediate complex regulatory tasks within the cell.

Pathways

Zinc Finger Protein 695 interacts with transcriptional regulation and signal transduction pathways. It has connections with the Wnt signaling pathway which is important for cell growth and development and may influence other proteins like β-catenin within this pathway. Additionally ZNF695 might be linked to the PI3K/Akt pathway which is important for regulating the cell cycle and preventing apoptosis. These associations suggest potential roles in maintaining cellular homeostasis and responses.

Abnormal expression or mutations in ZNF695 associates with certain types of cancer particularly breast and prostate cancer. There may be an interaction with the protein p53 a well-known tumor suppressor involved in cancer biology. Dysregulation of transcription factors like ZNF695 could lead to altered gene expression profiles contributing to oncogenesis. Understanding these connections may present opportunities for developing therapeutic targets or biomarkers.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information Zinc finger protein 695
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 25:105503 PubMed36404924

2022

Biofabrication of synthetic human liver tissue with advanced programmable functions.

Applications

Unspecified application

Species

Unspecified reactive species

Rodrigo M Florentino,Kazutoyo Morita,Nils Haep,Takashi Motomura,Ricardo Diaz-Aragon,Lanuza A P Faccioli,Alexandra Collin de l'Hortet,Zeliha Cetin,Carla Frau,Lawrence Vernetti,Anna-Klara Amler,Alexander Thomas,Tobias Lam,Lutz Kloke,Kazuki Takeishi,D Lansing Taylor,Ira J Fox,Alejandro Soto-Gutierrez
View all publications
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Product promise

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