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AB154640

Anti-ZNF83 antibody - N-terminal

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(2 Publications)

Rabbit Polyclonal ZNF83 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ZNF83 aa 1-150.

View Alternative Names

ZNF816B, ZNF83, Zinc finger protein 83, Zinc finger protein 816B, Zinc finger protein HPF1

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-ZNF83 antibody - N-terminal (AB154640)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-ZNF83 antibody - N-terminal (AB154640)

Immunofluorescent analysis of paraformaldehyde-fixed MCF7 cells labeling ZNF38 with ab154640 at a 1/1000 dilution.
The lower image has been stained with Hoechst 44432.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF83 antibody - N-terminal (AB154640)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNF83 antibody - N-terminal (AB154640)

Immunohistochemical analysis of paraffin embedded Huh-7 xenograft labeling ZNF83 with ab154640 at a 1/500 dilution.

Western blot - Anti-ZNF83 antibody - N-terminal (AB154640)
  • WB

Unknown

Western blot - Anti-ZNF83 antibody - N-terminal (AB154640)

7.5% SDS PAGE

All lanes:

Western blot - Anti-ZNF83 antibody - N-terminal (ab154640) at 1/1000 dilution

All lanes:

MCF7 whole cell lysate at 30 µg

Predicted band size: 60 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human ZNF83 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

P51522

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p>Alternatively Tris-EDTA buffer (pH8.0) may be used.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF83 also known as Zinc Finger Protein 83 is a protein with a molecular mass of approximately 70 kDa. It functions mechanically as a transcription factor facilitating the binding to specific DNA sequences through its zinc finger motifs. These motifs consist of sequences that enable ZNF83 to interact with DNA and regulate gene expression. The expression of ZNF83 is observed in various tissues with higher levels noted in certain regions of the brain including the cerebral cortex.
Biological function summary

ZNF83 plays a role in modulating gene transcription by binding to DNA influencing the expression of genes involved in multiple cellular processes. ZNF83 does not typically form part of a known multimeric complex but functions independently to regulate specific target genes. By controlling gene expression ZNF83 impacts cell differentiation and development with its activity being integral to normal developmental processes.

Pathways

ZNF83 interacts with gene regulatory networks important in cellular growth and development. Specifically it is associated with the Wnt signaling pathway a critical pathway that controls many aspects of cell fate determination cell migration and organogenesis. Within this pathway ZNF83 may interact with proteins such as β-catenin to exert its influence on gene expression impacting cell proliferation and differentiation.

ZNF83 links to certain neurological conditions due to its expression in the brain and its regulatory functions. Altered ZNF83 activity has been investigated in relation to schizophrenia where it might affect genes important for neuronal function and synaptic plasticity. Furthermore its connection to neurodegenerative disorders has been studied with proteins such as tau and amyloid precursor protein (APP) offering potential links through disrupted signaling pathways highlighting the significance of ZNF83 in neural health.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF83
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Discover oncology 16:1335 PubMed40663296

2025

Pan-cancer analysis and experimental validation revealed the prognostic role of ZNF83 in renal and lung cancer cohorts.

Applications

Unspecified application

Species

Unspecified reactive species

Peipei Wu,Yu Lin,Fang Dai,Huming Wang,Hantao Wen,Zihan Xu,Gengyun Sun,Zhaojie Lyu

Immunity, inflammation and disease 11:e829 PubMed37249295

2023

Myo-inositol oxygenase (MIOX) accelerated inflammation in the model of infection-induced cardiac dysfunction by NLRP3 inflammasome.

Applications

Unspecified application

Species

Unspecified reactive species

Wenjun Zhou,Congyi Yu,Yiwen Long
View all publications
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Product promise

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