Anti-ZNF85 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

ZNF85 also known as Zinc Finger Protein 85 functions as a DNA-binding transcription factor. It plays a critical role in regulating gene expression by binding to specific DNA sequences. ZNF85 is a protein weighing approximately 68 kDa. Researchers find it expressed mainly in the nucleus of cells with notable presence in tissues such as the brain and reproductive organs. This widespread expression suggests its role in various biological processes.

Biological function summary

Zinc Finger Protein 85 influences cellular activities such as cell differentiation and growth. It does not function as part of a large protein complex but acts independently to regulate specific target genes. Through its interaction with DNA ZNF85 modulates transcription and subsequently affects the cellular developmental processes. This regulation is essential for maintaining normal cellular functions and development.

Pathways

ZNF85 participates in signaling and regulatory pathways such as the Wnt signaling pathway. It interacts with other proteins like β-catenin impacting the transcriptional regulation within these pathways. In this context ZNF85 ensures the proper expression of genes involved in cellular signaling playing an important role in maintaining homeostasis and controlling cell proliferation.

Associated diseases and disorders

Research links ZNF85 to cancer and neurodegenerative diseases. Altered expression or mutation of ZNF85 contributes to abnormal cellular growth often seen in tumorigenesis. In cancer pathways it can interact with proteins such as p53 leading to disrupted cell cycle control. In neurodegenerative disorders changes in ZNF85 expression might cause disruptions in brain tissue potentially influencing the progression of diseases like Alzheimer's showing its importance in maintaining normal neurological function.