Supercharge your Alzheimer's Research

alzheimers research

Keep your Alzheimer’s disease research moving forward with the ultimate catalog of gold-standard, validated and cited recombinant antibodies and sensitive assays, including 384-well SimpleStep ELISA® kits that generate 300% more data from precious samples by using a quarter of the standard sample volume, delivering results in 90 minutes.

Powered by our recombinant technology, our reagents set you up for success in biomarker analysis with products that not only work first time, every time but consistently over time, thanks to our award-winning batch-to-batch biophysical quality control.

Browse our curated portfolio of extensively validated recombinant antibodies and assays sensitive to Tau, Beta-amyloid, and other Alzheimer’s targets of interest, with everything you need in one place.

Antibodies for Tau research

Untangle Tau research with our premium recombinant antibodies, designed for exceptional specificity and sensitivity. To get you the best reagents, we subject our antibodies to rigorous validation. We validate in blood and CSF samples, as well as AD patient samples, so you can test your precious samples with confidence.

Our broad range of antibodies offers sensitivity against a variety of Tau modifications. Effortlessly study all aspects of Tau phosphorylation with antibodies against different post-translationally modified sites.

Product highlights

Browse all our Tau tools: antibodies, kits, and matched antibody pairs

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Antibodies for Beta-amyloid research

Get high-quality antibodies to Beta-amyloid with unrivaled precision. Our antibodies undergo rigorous validation processes to ensure exceptional specificity and sensitivity, including in plasma, CSF, and Alzheimer’s patient samples.

With increasing evidence to support the biomedical importance of beta-amyloid (Aβ) structural variation, conformation-specific Aβ imaging reagents will play a central role in the future of Alzheimer’s research.

Target
Recommended product
abID
Human brain specificity shown by IHC*
AD mouse model brain specificity shown by IHC**
APP
Anti-Amyloid Precursor Protein antibody [Y188]
ab32136
Beta-amyloid
Anti-beta Amyloid antibody [2E9]
ab252816
Beta-amyloid 1-38
Anti-beta Amyloid 1-38 antibody [EPR1878(2)]
ab108253
Beta-amyloid 1-40
Anti-beta Amyloid 1-40 antibody [EPR23712-2]
ab254345
Beta-amyloid 1-42
Anti-beta Amyloid 1-42 antibody [EPR9296]
ab180956
Aggregated beta-amyloid fibrils
Anti-amyloid fibril antibody [mOC22] - conformation-specific
ab205339
Frontal cortex plaques
Layer V cortical and CA1 pyramidal neurons
Aggregated beta-amyloid (residues 2-6)
Anti-beta amyloid 1-42 antibody [mOC23] - conformation specific
ab205340
Subset of frontal cortex plaques
Hippocampal plaques
Vascular beta-amyloid
Anti-beta amyloid 1-42 antibody [mOC31] - conformation-specific
ab201059
Vascular amyloid deposits
Beta- amyloid (residues 3-6)
Anti-beta amyloid 1-4 antibody [mOC64] - conformation-specific
ab201060
Frontal cortex plaques
Aggregated beta-amyloid (residues 8-11)
Anti-amyloid fibril antibody [mOC78] - conformation specific
ab205341
Intracellular/nuclear, frontal cortex plaques
Layer V cortical neurons
Amyloid fibrils
Anti-amyloid fibril antibody [mOC87] - conformation-specific
ab201062
Frontal cortex plaques
Layer V cortical neurons (intracellular deposits)
Conformation-specific beta- amyloid
Anti-beta amyloid 1-42 antibody [mOC98] - conformation-specific
ab201061
Frontal cortex plaques
Layer V cortical neurons (intracellular deposits)

Antibodies to other Alzheimer’s disease targets

Explore our broad catalog of gold-standard recombinant antibodies to other AD targets of interest, including APOE, GFAP, and Neurogranin.

Product highlights

Target
Recommended product
abID
APOE4
Anti-Apolipoprotein E4 antibody [EPR24181-64]
ab279714
Presenilin-1/PSEN1
Anti-Presenilin 1/PS-1 antibody [EP2000Y]
ab76083
Presenilin-2/PSEN2
Anti-Presenilin 2/AD5 antibody [EP1515Y]
ab51249
β-secretase/BACE1
Anti-BACE1 antibody [EPR19523]
ab183612
TREM2
Anti-TREM2 antibody [EPR26209-22]
ab318262
GFAP
Anti-GFAP antibody [EPR1034Y]
ab68428
SNAP25
Anti-SNAP25 antibody [EPR3275]
ab109105
SORLA/SORL1
Anti-SorLA/SORL1 antibody [EPR23262-4]
ab302508
SV2A
Anti-SV2A antibody [EPR23500-32]
ab254351
Synapsin-1
Anti-Synapsin I antibody [EPR23531-50] - Synaptic Marker
ab254349
Neurofilament light/NEFL
Anti-68kDa Neurofilament/NF-L antibody [EPR22035-112]
ab223343
Neurogranin
Anti-Neurogranin antibody [EPR21152]
ab217672
Neurogranin truncated P75
Anti-Neurogranin (Trunc P75) antibody [EPR22522-19] - BSA and Azide free (Capture)
ab277261
Neuromodulin/GAP-43
Anti-GAP43 antibody [EP890Y] - Neuronal Marker
ab75810
S100 beta
Anti-S100 beta antibody [EP1576Y] - Astrocyte Marker
ab52642
Synaptophysin
Anti-Synaptophysin antibody [YE269]
ab32127
VILIP-1
Anti-VILIP1 antibody [EPR9832]
ab180141
TDP-43
Anti-TDP43 antibody [EPR5810]
ab109535
TDP-43 pS409+pS410
Anti-TDP43 (phospho S409 + S410) antibody [EPR24512-29] - BSA and Azide free (Capture)
ab317346
VEGF-A
Anti-VEGFA antibody [EP1176Y] - C-terminal
ab52917
CHI3L1/YKL-40
Anti-YKL-40/CHI3L1 antibody [EPR19078-157]
ab255297
IL1-β
Anti-IL-1 beta antibody [EPR21086]
ab216995
IL-6
Anti-IL-6 antibody [EPR21711]
ab233706
CCL2/MCP-1
Anti-MCP1 antibody [EPR21025]
ab214819
CCL11/Eotaxin
Anti-Eotaxin antibody [EPR5825]
ab133604
CX3CL1/Fractalkine
Anti-CX3CL1 antibody [EPR28004-7] - BSA and Azide free (Detector)
ab317057
TNF-α
Anti-TNF alpha antibody [EPR20972]
ab215188
TGF-β
Anti-TGF beta 1 antibody [EPR21143]Anti-DAP12 antibody [EPR24244-76]
ab215715
TYROBP/DAP12
Anti-DAP12 antibody [EPR24244-76]
ab283679
TYROBP/DAP12 (pY91)
Anti-DAP12 (phospho Y91) antibody [EPR25630-43]
ab314891

ELISA kits and matched antibody pairs

Get reproducible, batch-to-batch consistency using SimpleStep ELISA® kits for your biomarker research. Our highly sensitive ELISAs deliver consistent performance while reducing assay time to 90 minutes or less. They’re powered by our premium recombinant antibodies, delivering the sensitivity and specificity your samples deserve.

Growing numbers of our kits are now available in 10-pack sizes and a 384-well format, allowing you to get 300% more from your precious samples while using only a quarter of the sample volume.

Our carrier-free matched antibody pairs give you consistent, specific, and sensitive results. By creating your own ELISA, you can get unrivaled flexibility.

Here, we’ve highlighted some of our key products to support your research. Browse products related to key biomarkers, including Tau, LRKK2, TREM2, and important inflammatory cytokines.

Product highlights - First-to-market ELISA kit against phosphorylated Tau 217

Area
Target
ELISA kit
Matched antibody pair
Validated in CSF
Available in 384-well
Simple-Step®
Synaptic damage
SNAP25
ab256394
ab267669
*
Neurogranin
ab277083
ab253442
*
Neurogranin truncated P75
ab253471
*
GAP-43
ab282867
ab253637
*
Synaptophysin
ab315042
ab313706
*
Synapsin-1
ab308538
ab253633
*
Neuronal injury
Neurofilament light
ab288171
ab253512
*
VILIP-1
ab300324
ab253739
*
*
S100b
ab314846
ab244194
*
*
NSE
ab217778
ab244189
*
*
Protein misfolding
Tau
ab273617
ab253413
*
*
Tau (4R)
ab309282
ab309260
*
*
Tau pT217
ab318935
ab314557
*
N-368 Tau
ab315060
ab307114
*
*
Amyloid Precursor Protein
ab216944
ab241866
*
*
Beta amyloid 1-40
ab193692
Beta amyloid 1-42
ab289832
ab253583
Alpha-synuclein
ab260052
ab270346
*
Alpha-synuclein pS129
ab317050
*
TDP-43
ab282880
ab253540
*
TDP-43 pS409+pS410
ab317345
*
Inflammation
TREM2
ab224881
ab244027
*
*
CHI3L1/YKL-40
ab255719
ab305036
*
*
IL1-β
ab214025
ab241807
*
IL-6
ab178013
ab243973
*
*
*
IL-8
ab214030
ab241839
*
*
*
IFN-γ
ab236895
ab290008
*
CCL2/MCP-1
ab179886
ab241803
*
*
*
CCL11/Eotaxin
ab318938
ab317279
*
*
CX3CL1/Fractalkine
ab192145
ab317055
*
*
TNF-α
ab181421
ab213467
*
*
*
GFAP
ab288175
ab244094
*
*
DAP12
ab317544
ab290705
*
*
DAP12 (pY91)
ab316133
*
C1QA
ab300309
ab253876
*
*
Vascular deregulation
CRP
ab260058
ab270347
*
*
VCAM1/CD106
ab223591
ab271899
*
ICAM1/CD54
ab309172
ab288641
*
Flt-1/sVEGF-R1
ab289705
ab253794
*
VEGF-A
ab222510
ab312860
*
*
Pharmacodynamic biomarkers
LRKK2
ab315075
ab307747
*
Rab8
ab255718
ab256753
*
Rab10
ab255717
ab256752
*
Other
APLP1
ab309112
ab290703
*
*
APOE
ab108813
ab244096
*
BDNF
ab212166
*
*
Prealbumin/Transthyretin
ab231920
ab244071
*
*
*