High-quality reagents for autoimmune disease research
Autoimmune diseases occur when the body's immune system mistakenly attacks healthy cells, tissues, or organs. This abnormal immune response can lead to a variety of health problems, depending on which part of the body is targeted. Common autoimmune diseases include rheumatoid arthritis, lupus, multiple sclerosis, type 1 diabetes, and psoriasis, among others.
The exact cause of autoimmune diseases is not fully understood, but it is believed to involve a combination of genetic, environmental, and possibly other factors. Symptoms vary widely depending on the specific disease but often include inflammation, pain, fatigue, and organ dysfunction.
With the incidence of autoimmune diseases rising worldwide, research into translational immunology is becoming increasingly important, strengthening the demand for high-quality, specific biological reagents for research, drug discovery and diagnostics development.
Whether you’re trying to understand disease mechanisms, discover novel treatment strategies, or develop validated strategies for patient stratification for biologics treatments, we can support you with a broad, comprehensively validated portfolio covering key and emerging targets in autoimmune diseases.
Recombinant antibodies for autoimmune disease research
Our extensive range of recombinant monoclonal antibodies includes key targets involved in several autoimmune diseases, as well as our broad range of emerging biomarkers in IBD, psoriasis, rheumatoid arthritis, and lupus. These recombinant antibodies are validated across a range of different applications, including IHC-P, ICC/IF, flow cytometry, and Western blot analysis in human, mouse, and/or rat sample types. Using our recombinant monoclonal antibodies, you get our signature consistency, specificity, and reliability in your results.
We provide a large catalog of products for the customer's research needs for autoimmune diseases that are extensively validated, specific, and can be used in a range of applications.
Product highlights
Anti-IL-6 antibody [EPR21711]
- Validated across a range of different applications for human reactivity
- KO-validated
- Highly cited
- 5-star rated
Anti-Interferon gamma antibody [EPR23991-53]
- Validated across a range of different applications for human reactivity
- KO-validated
- 5-star review
- Highly cited
Anti-MCP1 antibody [EPR21025]
- Validated across a range of different applications for human reactivity
- KO-validated
- 5-star review
- Highly cited
Fluorescently labelled antibodies for autoimmune disease research
Our fluorescently labeled antibodies simplify protein analysis, saving you time and hassle in the lab.
We offer an ever-expanding range of fluorescence-conjugated antibodies to develop your multiplex panels. However, choosing the right antibodies and labels is crucial to avoiding problems like cross-talk and false-positive results.
Our conjugated antibodies take the guesswork out of the equation, providing you with fluorescence-conjugated antibodies that ensure sensitivity and specificity to deliver reliable results.
Fluorescence-labeled antibodies are critical for customers performing flow cytometry to understand and characterize the presence and identity of immune cells.
We have a wide range of conjugated and/or unconjugated antibodies that have been validated in flow cytometry. Additionally, using our Lightning-Link® kits, you can choose your own combination of fluorescence tag and antibody.
Product highlights
Alexa Fluor® 488 Anti-T-bet / Tbx21 antibody [EPR27094-16]
- Validated in flow cytometry
- Highly specific
- Available in other conjugate formulations
Alexa Fluor® 647 Anti-IL-6 antibody [EPR21711]
- Validated in flow cytometry
- Highly specific
- Available in other conjugate formulations
PE Anti-IL-10 antibody [EPR1114]
- Validated in flow cytometry
- Highly specific
- Available in other conjugate formulations
ELISA kits for autoimmune disease research
ELISA kits contain all the reagents and tools you need to perform an ELISA, which is the most commonly used method for the detection and measurement of the presence of antigens in biological samples. Our ELISA kits use high-quality and specially matched antibody pairs as the basis, giving you reliable and reproducible results over time.
With our easy-to-use, single-wash SimpleStep ELISA® kits, you can go from sample to results in just 90 minutes. Made with recombinant monoclonal antibody pairs, they offer the highest sensitivity, specificity, and consistency. With our new 10-pack sizes, it's quick and easy to scale up your experiment.
ELISA kits are a fast way to measure biomarkers in a plate-based assay for screening.
Our ELISA kits have a broad dynamic range and are validated in a large variety of sample types.
Product highlights
Human IL-6 ELISA Kit
- Single wash, 90min protocol
- 7.8-500 pg/ml dynamic range
- Validated in a broad range of sample types
Human IFN gamma ELISA Kit
- Single wash, 90 min protocol
- 0.468-30 ng/ml dynamic range
- Validated in a broad range of sample types
Human Oncostatin M/OSM ELISA Kit
- Single wash, 90 min protocol
- 15.625-1,000 pg/ml dynamic range
- Validated in a broad range of sample types