ChIP-Seq solutions
Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) is a powerful technique that identifies binding sites of DNA-associated proteins across the entire genome. By combining chromatin immunoprecipitation with next-generation sequencing, ChIP-Seq provides high-resolution insights into protein-DNA interactions, gene regulation, and chromatin structure.
The success of ChIP-Seq relies heavily on the quality and specificity of the antibodies used. These antibodies are essential for the immunoprecipitation step, where they selectively bind to the target protein associated with the DNA. High-quality antibodies ensure the enrichment of the desired protein-chromatin complexes, leading to accurate identification of binding sites.
Our extensive range of ChIP-Seq-validated recombinant monoclonal antibodies offers both accuracy and reproducibility. Powered by our recombinant technology, our reagents set you up for success with products that not only work first time, every time but consistently over time, thanks to our award-winning biophysical quality control.
ChIP-Seq validated recombinant monoclonal antibodies
Our premium recombinant monoclonal antibodies are meticulously tested to ensure they deliver reliable and accurate results in ChIP-Seq applications. By choosing our antibodies, you can trust in their specificity and consistency for identifying protein-DNA interactions. Our rigorous batch-to-batch quality control guarantees reproducible results, enabling you to advance your research with precision and confidence.
We offer antibodies validated in Chip-Seq targeting a broad spectrum of proteins:
1. Histones: essential for studying chromatin structure and modifications
2. Transcription Factors: essential for studying cellular states and processes
o c-Myc: A transcription factor involved in cell cycle progression, apoptosis, and cellular transformation.
o HIF-1 alpha: A transcription factor that responds to changes in available oxygen in the cellular environment, crucial for hypoxia response.
o MASH1/Achaete-scute homolog 1 (ASCL1): A transcription factor important for neuronal differentiation.
o Oct4 (POU5F1): A transcription factor essential for maintaining the pluripotency of embryonic stem cells.
o HNF-4-alpha: A transcription factor that regulates the expression of genes involved in liver and pancreatic function.
3. Control Antibodies (IgG): Our control antibodies, such as IgG, are essential for validating the specificity of your ChIP-Seq experiments.
Product highlights
Anti-Histone H3 (acetyl K27) antibody [EP16602] - ChIP Grade
- Cited in over 75 publications
- Tried and trusted by researchers since 2010
- Affinity purified using Protein A
- Recombinant format for unrivaled batch-batch consistency: no need for same-lot requests
Anti-c-Myc antibody [Y69] - ChIP Grade
- Cited in over 1315 publications
- Specificity confirmed with MYC knockout cell line validation
- Recombinant format ensures unrivaled batch-to-batch consistency; no need for same-lot requests
- Antibody clone Y69 has been tried and trusted by researchers since 2006
Histone antibodies
Transcription factor antibodies
Control antibodies
ChIP-Seq kits
In addition to individual antibodies, we provide comprehensive kits that include all the necessary reagents for your ChIP-Seq experiments. These kits are designed to streamline your workflow and ensure consistent, high-quality results.