Fluid biomarkers are measurable biological molecules found in bodily fluids like blood, urine, cerebrospinal fluid (CSF), and saliva. These biomarkers provide valuable insights into physiological and pathological processes by indicating normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. They also play a pivotal role in clinical trials by serving as endpoints to measure the efficacy and safety of new therapies.

Immunoassaysare essential tools in fluid biomarker research due to their high sensitivity and specificity. These assays use antibodies to detect and quantify biomarkers in the various bodily fluids cited above. By enabling precise and reliable biomarker detection, immunoassays play a pivotal role in both basic research and clinical applications, facilitating the development of new diagnostic and therapeutic strategies.

Biochemical and metabolism assays measure the functional activity of enzymes or other proteins, offering insights into biological processes and disease mechanisms. Combined with immunoassays, these assays paint a more complete picture of a biomarker's role in physiology and disease.

Carrier-free matched antibody pairs

Whether you need to customize, upscale or adapt your immunoassay on a different platform, you can choose from our broad range of over 1,800 carrier-free antibody pairs.

Our pairs are free from preservative and therefore ready for conjugation. Most importantly each pair has been highly validated and selected for the best specificity and sensitivity. We provide these pairs as individual capture and detector antibodies. You can complete your experiment with our Lightning-Link® conjugation kits or for convenience use our biotinylated detector antibodies.

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SimpleStep ELISA^® kits

SimpleStep ELISA® kits are ready-to use and generate results in just 90 minutes thanks to a standardized single-wash “mix-wash-read” protocol, cutting your assay time down by several hours compared to traditional ELISA kits.

Our kits are available as sandwich or competitive assays and are powered by our highly validated recombinant monoclonal antibodies for high sensitivity, specificity and reproducibility. Our sandwich SimpleStep ELISA^® kits are also available in bulk sizes (10 x 96 plates) or high-throughput 384 well format to get even more results in 90 minutes. Our range of over 1,500 SimpleStep ELISA^® kits is continuously expanding to provide the kits you need for your research.

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Protein standards

Protein standards are essential references and tools, used in immunoassays to generate a standard curve and quantify the concentration of the target protein in a sample.

Our protein standards perfectly complement our existing immunoassay solutions (SimpleStep ELISA® kits and carrier-free antibody pairs). They are characterized and validated with SDS-PAGE and sandwich ELISA assays using the corresponding capture and detector antibodies.

Our protein standards are:

-          Recombinant proteins

-          Animal-free

-          Research grade (Purity >=80% SDS-PAGE)

-          Cover a range of mammalian species including human, mouse and rat

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Biochemical and cellular assays

Biochemical assays measure and can be used to understand biochemistry and protein biology, eg quantify metabolites or measure enzyme activity. In the broadest sense, biochemical assays are all assays that measure proteins and biochemistry.

Our cellular metabolism assays are easy-to-use, optimized kits that can be used to test metabolism connections faster across a wide range of disease areas and metabolic events. Abcam has 20 years of experience in manufacturing metabolism assay kits, so we can help you understand your cell or disease model or how your target or compound affects your metabolic pathway/phenotype of interest.

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