Move Fast In Glioblastoma with IHC antibodies to >90% GBM targets
Set yourself up for success with the world’s largest range of quality, precision antibodies and assays. As the proud winners of the 2024 CiteAb award for Supplier Succeeding in IHC, we’re committed to providing you with the best reagents for biomarker discovery and validation.
Our recombinant antibody technology means our reagents work first time, every time, and over time, giving your research the reliable tools it deserves.
Browse our curated portfolio of extensively validated antibodies and assays, with antibodies to over 90% of key targets in major glioblastoma pathways– including EGF, VEGF, MAPK, Wnt, NFKB, and PI3K/AkT/MTOR – all in one place.
IHC-validated recombinant antibodies
Analyze your precious glioblastoma samples with confidence with our award-winning recombinant antibodies, designed for exceptional specificity and sensitivity. We know how important it is that you can trust your reagents, which is why we offer over 12,000 recombinant antibodies fully validated in IHC to help de-risk your antibody selection. We validate our antibodies in tissue microarrays (TMAs) comprising 16 human normal and 16 human cancer tissue cases as well as TMAs of normal mouse and rat tissue. Where relevant, we test antibodies to glioblastoma targets in human glioma tissue to guarantee sensitivity and specificity in your tissue of choice.
Our enhanced validation program goes above and beyond, validating some of our best recombinant antibodies in a vastly increased number of cancer tissue cases and assays. Using FFPE cell lines with modulated target expression, peptide blocking assays, ELISA, and other bespoke assays, our enhanced validation provides ultimate confidence in an antibody clone. Up to 600 different disease cases are used to generate a detailed antibody expression profile, and antibody sensitivity is evaluated with manual and digital target staining intensity analysis.
Our antibodies are compatible with a range of high- and low-plex multiplexing technologies. Our range includes >350 recombinant antibodies validated in-house in mIHC (multiplex IHC) using Opal™ (Akoya Biosciences) detection kits and the BOND™ RX (Leica®), including key glioblastoma targets to simplify panel building. Our conjugation-ready carrier-free formats harmonize with leading spatial platforms, including those supplied by Nanostring and Akoya. The GeoMx® IO Proteome Atlas, powered by >570 IHC-validated Abcam antibodies, is the most comprehensive spatial proteomics assay available to date.
Product highlights
Anti-EGFRvIII antibody [EPR28380-83]
- Enhanced Validations in multi normal and gliomaTMAs
- Validated in a multiplex chromogenic assay
- Available in carrier-free and conjugated formats
Anti-IDH1 antibody [EPR21002]
- Knock-out validated
- Validated for IHC in gliobalstoma tissue
- Available in carrier-free and conjugated formats
Anti-GFAP antibody [EPR1034Y]
- Knock-out validated
- Validated for IHC in gliobalstoma tissue
- Available in carrier-free and conjugated formats
BOND is a trademark of Leica Biosystems and its affiliates. GeoMx is a registered trademark of Bruker Spatial Biology, Inc.
Cell-type antibodies
We’ve gathered our best antibodies to key cell-type markers so you can phenotype neuron and glial cell types with confidence. You can also analyze the proliferation status and epithelial-to-mesenchymal transition of cells within the glioblastoma tumor microenvironment. Get more from your imaging analyses with our premium recombinant antibodies.
Product highlights
Anti-Ki67 antibody [SP6]
- Highly cited
- Validated for mIHC in human cerebellum tissue
- >100 five star reviews
Anti-Vimentin antibody [EPR3776] - Cytoskeleton Marker
- Highly cited
- Validated for mIHC
- Validated in multi-normal and multi-tumor TMAs
- Covers broad applications and species
Anti-N Cadherin antibody [EPR1791-4]
- Highly cited
- KO validated
- Available in carrier-free and conjugated formats
SimpleStep ELISA® kits
Our SimpleStep ELISA® kits give you speed and simplicity without compromising on performance. Their single-wash protocol gives you results in just 90 minutes, halving the time of a traditional ELISA. Powered by our recombinant antibodies, our SimpleStep ELISA® kits deliver exceptional sensitivity, specificity and reproducibility.
To support all your experiments, great and small, our kits are available in 96- and 384-well formats, with our 96-well plate breakable into 12 x 8 strips. We also provide 10-pack sizes. Our 384-well format uses a quarter of the sample volume compared to our 96-well kits, allowing you to get the most data possible from your precious samples.
Product highlights
Human MGMT ELISA Kit (ab320053)
- One of the fastest single-wash ELISAs to this target
- Compatible with cell lysate and tissue extract samples
- 96- and 384-well formats available
- Superior sensitivity
- Results in 90 minutes
pan-HMR VEGFC ELISA Kit (ab315050)
- New product
- Pan-reactivity to human, mouse and rat samples
- Compatible with serum, heparin plasma, EDTA plasma, citrate plasma, and cell culture supernatant
Human IL-23 ELISA Kit (ab221837)
Compatible with cell culture media, heparin plasma, citrate plasma, serum, and EDTA plasma human samples
