IHC antibody solutions

Man pippetting in the lab

Immunohistochemistry (IHC) is an immunostaining technique which selectively identifies antigens in tissues. High-quality, specific antibodies are essential to run a successful IHC experiment.

IHC is widely used in research and diagnostics to study the pathophysiology of both normal biological processes and disease states. IHC is routinely used in histopathology to detect the presence and localization of specific protein markers within a patient tissue sample. This is critical to enable accurate diagnosis, tumor classification, prognosis and treatment plans.

Abcam’s catalog offers an extensive portfolio of IHC antibodies validated to the highest industry standards to allow your research to move faster.

Recombinant antibodies

IHC has become an essential technique in clinical diagnostics. Robust, reliable, and reproducible antibodies are essential for running good IHC experiments. Our portfolio of recombinant rabbit antibodies offers over 8,700 antibodies, including the broadest range of IHC antibodies in the immuno-oncology field

Our antibodies are validated in IHC with industry-leading processes so you can trust your reagents and your results. Antibodies are tested—during clone screening as well as final QC stages—on tissue microarrays (TMAs) comprising over 15 human normal tissue types and 15 human cancer types, all in duplicates. For markers of clinical relevance, disease-specific TMAs are also used as part of the validation process (eg breast cancer TMAs including different cancer subtypes like carcinoma, adenocarcinoma, invasive ductal carcinoma etc). Mouse and rat tissues are also included to assess species cross-reactivity where needed.

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Browse our full range of recombinant antibodies validated in IHC

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Multiplex-ready antibodies

IHC is a powerful widely used diagnostic tool in histopathology, but analysis is limited to only one marker per tissue section. Multiplex IHC (mIHC) combines the power of IHC with the ability to image several markers within the same tissue section.

The extensive validation of our portfolio of recombinant IHC antibodies ensures that our products are compatible with many mIHC platforms (eg Akoya, Nanostring, 10X Genomics).

We also offer a large portfolio of IHC-validated antibodies conjugated with fluorescent dyes that allow staining of multiple markers on the same tissue section without the need for a secondary antibody, streamlining the protocol and saving you time.

Find out how Abcam’s antibodies were used in a 40-plex antibody panel to study spatial architecture in glioblastoma.

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Explore our range of over 400 antibodies compatible with mIHC

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Antibody panels

Abcam's antibody panels offer reliable, high-quality tools to support various research applications. Designed to streamline the study of biological markers and pathways, our panels are ideal for investigating cellular processes, disease mechanisms, and therapeutic targets. Whether focused on exosomes, stem cells, immune cells, or signaling pathways, these products give you ready-to-use solutions to achieve accurate and reproducible results.

Validated for performance and covering a broad spectrum of targets, Abcam's panels ensure confidence in experimental outcomes. With options suitable for human and mouse models, they cater to diverse research needs. By combining quality, ease of use, and comprehensive coverage, these panels are a valuable tool in your arsenal.

Product highlights

Product name
abID
Included markers
Applications
Autophagy Marker (APG5L/ATG5, ATG16L1, ATG4B, ATG9A, Beclin 1, LC3B) Antibody Sampler Panel
ab228525
APG5L/ATG5, ATG16L1, ATG4B, ATG9A, Beclin 1, LC3B
Studying autophagic processes, cellular homeostasis; neurodegenerative diseases and cancer research
Fibroblast Marker (Vimentin, alpha smooth muscle Actin, Hsp47, S100A4) Antibody Panel - Human, Mouse
ab254015
Vimentin, alpha smooth muscle actin, Hsp47, S100A4
Identification of fibroblast populations; research on tissue repair and fibrosis in human and mouse models
Mature Oligodendrocyte Marker (Olig2, MBP, MOG, SOX10) Antibody Sampler Panel - Human, Mouse
ab254026
Olig2, MBP, MOG, SOX10
CNS research focusing on myelination and demyelinating diseases in human and mouse models
Plasma Membrane Marker (Na/K ATPase, pan Cadherin, PMCA1) Antibody Sampler Panel - Human, Mouse
ab254025
Na/K ATPase, pan Cadherin, PMCA1
Studying membrane proteins, cellular signaling, and dynamics in human and mouse cells
Macrophage Marker (CD11b, CD68, CD163, CD14, CD16) Antibody Panel - Human
ab254013
CD11b, CD68, CD163, CD14, CD16
Research on macrophage polarization, immune responses; immunology and inflammation studies
Microglia Marker (CD11b, CD45, Iba1, TMEM119) Antibody Sampler Panel
ab226482
CD11b, CD45, Iba1, TMEM119
Investigating microglial function in the brain; neuroinflammation and neurodegenerative disease research
EMT Marker / Epithelial to Mesenchymal Transition Marker Panel
ab216833
Epithelial-to-mesenchymal transition markers
Research on cellular plasticity, tumor metastasis; cancer progression and fibrosis studies
Mesenchymal Stromal Cell Marker (CD44, CD45, CD90 CD29, CD105) Antibody Panel - Human
ab93758
CD44, CD45, CD90, CD29, CD105
Identification of mesenchymal stromal cells in human models; stem cell therapy and regenerative medicine research

Browse our full range of multiplex-ready antibody panels

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