Tools to support your neuroinflammation research
Get to the root cause of neurodegeneration with our curated range of gold-standard recombinant antibodies and immunoassays to detect glia, aggregated proteins, and proinflammatory mediators in neurodegenerative disorders. Our range of 32,000 precision recombinant antibodies provide unrivaled sensitivity, giving your precious samples the reagents they deserve.
Browse our unbeatable portfolio of extensively validated antibodies and assays, with all the tools you need in one place.
Label astrocytes and microglia
Easily label microglia and astrocytes with our versatile range of glial marker antibodies. Our premium recombinant antibodies are validated in relevant tissue samples, including brain tissues, cell cultures and iPSCs, and applications including IHC-P and IHC-Fr. Where relevant, we validate our antibodies using patient samples so you can test your precious samples with confidence. We offer a broad range of pre-conjugated antibodies, including to fluorophores including Alexa Fluor® dyes, but if those don’t meet your needs, we’ve reformulated over 10,000 of our antibodies to be carrier-free so you can adapt your antibody to a conjugate of your choice. Browse our curated product range below.
Product highlights
Anti-GFAP antibody [EPR1034Y]
- Broad coverage of reactivity to human, mouse and rat tissues for mIHC, IHC-P, IHC-Fr, ICC, IP, WB, and flow cytometry
- Validated with human cerebellum tissue
- 14 five-star reviews
Anti-Iba1 antibody [EPR16588] - Goat IgG (Chimeric)
- Goat recombinant monoclonal antibody
- Ideal to multiplex or co-stain with other host species for ultimate flexibility
Anti-TMEM119 antibody [28-3] - Microglial marker
- Top-cited TMEM119 antibody on the market
- Knock-out validated
Browse our comprehensive marker guides to help you quickly find the right reagents for your target of interest.
Study aggregated and misfolded proteins
Enhance your study of misfolded proteins with near-infrared (NIRF) probes and antibodies against post-translational modifications and conformational variants. Our portfolio includes reagents to a broad range of targets, including to modified forms (eg post-transcriptional modifications and aggregates) and unmodified forms. We validate our premium antibodies with relevant samples, including normal and disease brain tissue, and relevant applications including IHC-P and IHC-Fr.
Product highlights
Anti-Alpha-synuclein antibody [MJFR1]
- Developed in partnership with the Michael J Fox Foundation
- Validated in PD patient samples
Anti-Tau Alzheimer’s Disease antibody [GT-38] - Conformation-Specific
- Conformation-specific to co-occuring 3R and 4R isoforms for AD pathology specificity
- Validated in AD patient samples
Anti-Amyloid Fibril antibody [mOC22] - Conformation-Specific
- Detects a confirmation-dependent and aggregation-specific generic fibril epitope
- Stains misfolded or aggregated intraneuronal amyloid deposits
Detect proinflammatory mediators
Dissect the role of pro-inflammatory mediators in neurodegenerative disease with our ELISA kits. Our SimpleStep® ELISA kits halve the time of a traditional ELISA kit without compromising on performance, delivering results in just 90 minutes thanks to their simple one-wash protocol. Powered by recombinant antibody technology, our SimpleStep® ELISA kits give you unbeatable sensitivity, specificity and reproducibility. We validate our kits in relevant sample types, including biofluids like plasma and cerebrospinal fluid.
To give you the most flexibility possible our kits are available in 96- and 384-well formats. Our 384-well format uses a quarter of the sample volume compared to our standard kit, letting you get the most data possible from your precious samples. For smaller experiments, the 96-well plate is breakable into 12 x 8 strips. 10-pack sizes are also available.
Product highlights
Human TREM2 ELISA Kit
- 78.1-5000 pg/mL
- Validated in CSF, plasma and serum
Human IL-6 ELISA Kit
- 7.8-500 pg/mL
- Knock-out validated
- Validated in CSF, plasma and serum
Human TNF alpha ELISA Kit
- 15.63-1000 pg/mL
- Knock-out validated
- Validated in CSF, plasma and serum
Antibody sampler panels
Derisk antibody selection and save time searching for the right reagent with our antibody sampler panels. Each panel contains 10 µl aliquots of at least four different antibody clones to key disease targets.
Product highlights
Microglia Marker (CD11b, CD45, Iba1, TMEM119) Antibody Sampler Panel
- Four microglia markers
- Image shows mouse brain tissue labeling Iba1 with ab178846
Astrocyte Marker (ALDH1L1, EAAT1, EAAT2, GFAP) Antibody Sampler Panel
- Four astrocyte markers
- Image shows mouse cerebellum tissue lysate labeling GFAP with ab68428
Neuroinflammation Marker (BDNF, ICAM1, TREM2, GFAP, TNF alpha, Iba1) Antibody Panel – Human
- Six key neuroinflammation markers
- Image shows normal human brain tissue labeling GFAP with ab33922
Conformation-Specific Amyloid beta Antibody Sampler Panel
- Eight conformation-specific amyloid beta clones
- Image shows human Alzheimer’s disease brain tissue labeling amyloid fibrils with ab205341
