Organelle markers and dyes for imaging applications
Imaging applications, like IHC, ICC/IF and live cell imaging, allow you to track the location and movement of specific proteins within the cellular environment. To interpret your experiments accurately, it’s important to use reliable reagents that identify cellular landmarks to locate your target of interest.
Organelle-specific antibodies, dyes and stains can be used to confirm a protein’s sub-cellular localization. Abcam offers a broad range of highly-cited organelle-specific reagents that offer high sensitivity, flexibility, and spectrum coverage. Explore our range of organelle-specific antibodies and dyes below and discover why our reagents are deeply trusted by cell biologists.
Organelle markers
Our broad catalog of gold-standard antibodies features over 60 targets for organelles and cellular structures. These include markers for the nucleus (eg LaminB1), endoplasmic reticulum (eg Calreticulin), Golgi apparatus (eg GM130), mitochondria (eg TOMM20), ribosomes (eg RPS3), endosomes (eg CD63), peroxisomes (eg Catalase) and autophagosomes (LC3B).
Our recombinantly manufactured antibodies offer ultimate sensitivity, specificity and reliability, giving you confidence in your results. Our antibodies are broadly validated across relevant applications, including IHC, ICC/IF, WB and flow cytometry. Browse our curated range of antibodies and discover the best tools for your targets of interest.
Product highlights
Anti-GM130 antibody [EP892Y] - cis-Golgi Marker
- 294 citations
- 5* rating with 38 reviews
- Available in carrier-free and conjugated formats for all commonly-used dyes
Anti-LC3B antibody [EPR18709] - Autophagosome Marker ()
- 468 citations
- 5* rating with 17 reviews
- KO validated
Anti-Calnexin antibody - ER Marker
- 483 citations
- 5* rating with 28 reviews
- KO validated
Cytopainter organelle dyes
At Abcam, we offer more than just antibodies. Our cytopainter dyes are ideal for working with live cells; they stain subcellular compartments from the nucleus to mitochondria and the endoplasmic reticulum, facilitating morphology and distribution studies. Their retention after cell fixation means they can also be used as co-stains alongside antibodies, letting you visualize even more proteins at once in studies of fixed cells.
Our dyes are easy to integrate into your existing staining protocols and have high photostability to provide longer exposure times.
Product highlights
Cell Tracking Dye Kit - Green – Cytopainter
- Unform cell labeling for multicolor analysis
- Robust labeling process, requiring minimal hands-on time
- Can be used with multiple fluorescent readouts, including flow cytometry and microscopy
ER Staining Kit - Red Fluorescence – Cytopainter
- Suitable for live cell or detergent-permeabilized aldehyde-fixed cell staining
- Designed for use with GFP-expressing cell lines or cells expressing blue, cyan or yellow fluorescent proteins
- Usable in combination with other common UV and visible light fluorescent dyes in multi-color imaging
Cell Plasma Membrane Staining Kit
- Uniform staining across various mammalian cell types
- Staining remains after fixation with formaldehyde, enabling further multicolor staining
Nuclear dyes for staining fixed and live cells
Our range of dyes for nuclear staining, including commonly-applied dyes like DAPI, Hoechst and propidium iodide, has broad compatibility for live and fixed cell staining. DRAQ5™ and DRAQ7™ dyes allow for rapid staining of dsDNA and support multi-color analysis by flow cytometry, laser scanning cytometry and confocal microscopy. Our dyes are compatible with a wide range of applications, including ICC/IF, and can be used to understand tissue architecture and quantify cells.
Product highlights
DRAQ5™
- Cell permeable far-red fluorescence DNA dye
- Can be used in fixed or live cells in combination with common labels like GFP and FITC
DRAQ7™
- Selectively stains the nuclei of dead and permeabilized cells; can be used in place of for propidium iodide
- Can be used in combination with common labels like GFP and FITC
- Rapid staining with no wash needed
