Tools to support your Parkinson’s disease research

We believe that we go further, faster, when we go there together. That’s why we partnered with The Michael J. Fox Foundation For Parkinson’s Research (MJFF) to develop precision rabbit monoclonal antibodies against promising targets and move Parkinson’s disease (PD) research forward.
The MJFF is dedicated to finding a cure for PD through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. Over 150 products for PD research have been produced as part of the MJFF-Abcam collaboration. These research tools include market-leading reagents and cover key PD targets including LRRK2, a-Synuclein, DJ-1, PINK1 and Rab GTPases. Learn about The MJFF, our collaboration, and the antibodies we’ve developed together in order to give you the edge in your research.
LRRK2 antibodies
Don’t waste time with poor-quality LRRK2 antibodies. We’re proud to collaborate with the Michael J. Fox Foundation to develop precision antibodies that deliver the specificity your research deserves. Our broad range features reagents to modified and unmodified LRRK2 so you can find the right tools for your experiments.
"LRRK2 antibodies are critical to help move Parkinson's research forward. The… unique clones chosen for initial release were identified based on several months of testing by our large network of Parkinson’s researchers... we are excited that they [Abcam] will continue to help MJFF remove barriers to developing Parkinson's therapies."
- Dr Mark Frasier, Vice President of Research Programs at MJFF
Product highlights
Anti-LRRK2 antibody [MJFF2 (c41-2)]
- The most-cited reagent to LRRK2 available
- Knock-out validated
- Developed with MJFF

Anti-LRRK2 (phospho S935) antibody [UDD2 10(12)]
- >100 citations
- Developed with MJFF
- Suitable for studying protein phosphorylation

Anti-LRRK2 (phospho S1292) antibody [MJFR-19-7-8]
- >50 citations
- Developed with MJFF
- Suitable for studying protein phosphorylation

α-Synuclein reagents
Browse our range of fully validated, precision antibodies to the most promising Parkinson’s disease target. Our curated range includes reagents to unmodified, modified and aggregated α-Synuclein so you can find the best tools for your research.
Product highlights
Anti-Alpha-synuclein antibody [MJFR1]
- >200 citations
- Developed with MJFF
- Knock-out validated
- Validated with Parkinson’s disease samples

Anti-Alpha-synuclein (phospho S129) antibody [EP1536Y]
- The most-cited reagent to α-synuclein available
- Suitable for studying protein phosphorylation
- Validated with Parkinson’s disease samples

Anti-Alpha-synuclein aggregate antibody [MJFR-14-6-4-2] - Conformation-Specific
- >100 citations
- Developed with MJFF
- Specifically labels aggregated α-synuclein
- Validated with Parkinson’s disease samples

Rab GTPase antibodies
Browse our gold-standard antibodies to various members of the RAB protein family, including Rab8A, Rab10 and Rab29. Our broad range includes phospho-specific antibodies that can be used to assess LRRK2 activity and the impact of LRRK2 inhibitors.
Product highlights
Anti-RAB8A (phospho T72) antibody [MJF-R20]
- The most-cited reagent to study RAB8A pT72 available
- Developed with MJFF
- Suitable for stud
- Phospho-specificity was demonstrated with LRRK2 [R1441C] knock-in MEF lysates

Antibodies to other PD targets
Browse our curated range of precision antibodies to complementary targets, including emerging markers.
Product highlights
Anti-Parkin (phospho S65) antibody [MJF-R17-42-4]
- Developed with MJFF
- Suitable for studying protein phosphorylation
- Phospho-specificity confirmed by cell depolarization

Anti-Ubiquitin (phospho S65) antibody [30H3/30K1
- Developed with MJFF
- Suitable for studying protein phosphorylation
- Specificity confirmed by mitochondrial uncoupling with CCCP

Anti-GBA antibody [EPR5142]
- Knock-out validated
- The most-cited rabbit monoclonal antibody to this target available
- Validated with brain tissue
