Tools for your stroke research

Stroke is the second leading cause of mortality worldwide, accounting for 12% of all deaths. It’s also a major risk factor for the development of vascular cognitive impairment (VCI), vascular dementia (VaD), and Alzheimer’s disease (AD): current evidence suggests that 25-30% of ischemic stroke survivors develop immediate or delayed VCI or VaD.
Stroke’s complex pathology demands exacting reagents. Explore our catalog of gold-standard antibodies and assays to access the tools you need to advance your research in stroke and its associated diseases.
Key targets in stroke research
Genomic studies have implicated several key targets in stroke, including HTRA1, NOTCH3, COL4A1/2, VEGFA, ACHE and BCHE. We offer a broad range of premium recombinant antibodies to these targets, broadly validated across relevant applications and sample types. Recombinant technology guarantees ultimate reproducibility and unrivaled specificity to give you the best tools possible.
Product highlights
Anti-VEGFA antibody [EP1176Y] - C-terminal
- Cited in over 200 publications
- Validated for ICC/IF, flow cytometry and IHC-P
- Reacts with human and mouse samples

Anti-VCAM1 antibody [EPR5047]
- Cited in over 300 publications
- Broadly validated in IHC-P, IP, ELISA, WEB, ICC/IF and flow cytometry (intra)
- Reacts with human, mouse and rat samples
- Knock-out validated

Autophagy antibodies
Autophagy has a neuroprotective effect in ischemic stroke, contributing to the regulation of neuronal cell survival and death. Understanding the role of autophagy in the pathogenesis of ischemic stroke is an exciting avenue for the discovery of new biomarkers and development of new treatments.
Our broad range includes some of the most highly cited antibodies in autophagy pathway study. Our portfolio includes precise, highly-validated antibodies raised against key pathway components like ATGs, LC3B, p62/SQSTM1 and Beclin-1.
Product highlights
Anti-LC3B antibody [EPR18709] - Autophagosome Marker
- Rabbit monoclonal antibody validated for WB, IHC and ICC/IF
- Reacts with human, mouse and rat samples
- Validated with multi-tissue microarrays including human brain samples
- Knock-out validated
- Cited in over 570 publications

Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker
- Suitable for IP, WB, ICC/IF, flow cytometry
- Reacts with human, mouse and rat samples
- Knock-out validated
- Cited in over 440 publications

Diagnostic biomarker ELISA kits
Diagnostic stroke biomarkers can be used to differentiate between ischemic and hemorrhagic strokes, which require distinct treatment approaches. Diagnostic stroke biomarkers can also distinguish between ischemic strokes and stroke mimics like migraine, seizure, or hypoglycemia. Finally, biomarkers can identify the etiological subtype of ischemic strokes, essential because prognosis, recurrence risk and management options differ greatly between subtypes.
Advance your research with our SimpleStep ELISA® kits for diagnostic stroke biomarkers. Our kits give you ultimate speed and simplicity without compromising on quality. Their one-wash protocol delivers results in 90 minutes to save you time at the bench, and recombinant technology delivers superior specificity and reproducibility. Where relevant, we validate our kits in cerebrospinal fluid (CSF) to guarantee compatibility with your samples.
Product highlights
Human IL-6 ELISA Kit
- Quantify human IL-6 with a sensitivity of 1.6 pg/ml
- Easy-to-use, rapid and sensitive ELISA
- Colorimetric assay usable with any plate reader
- 10-packs available for bulk orders and 384-well format available for higher throughput

Prognostic biomarker ELISA kits
Prognostic stroke biomarkers can accurately predict mortality risk, functional outcomes and specific complications after stroke like post-stroke cognitive impairment.
Explore prognostic biomarkers in stroke with our range of precision ELISA kits, including SimpleStep ELISA® kits that deliver accurate, reproducible results in 90 minutes. Our portfolio includes kits to relevant targets like BDNF, IGF1, IL-33, PEDF and SPARC.
Product highlights
Human BDNF ELISA Kit
- Single-wash, 90-minute rapid ELISA that quantifies human BDNF
- Validated with CSF, heparin plasma, citrate plasma, cell culture supernatant, serum, and EDTA plasma samples
